Protective Effects of Welsh Onion (Allium fistulosum L.) on Drug-induced Hepatotoxicity in Rats

Cha, Hwan-Soo; Seong, Ki-Seung; Kim, Sung Hoon; Seo, Ji-Woo; Park, Sunjoo; Kim, Soon-Im; Lee, Kyung-Won; Yoon, Sorah; Han, Dong-Un

doi:10.3746/jkfn.2005.34.9.1344

Cited by 1 publication

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“…대파의 생리 활성에 관한 연구는 약물성 간장 장해에 대한 대파의 보호 효과 (Cha et al, 2005), 대파로부터 분리한 fistulosides의 항진 균 활성 (Sohn et al, 2006), 대파로부터 분리한 cinnamic acid의 free radical 소거 활성 (Seo et al, 2011), 항인플루엔자 바이러스 효과 (Lee et al, 2012), 대파의 대장암 억제 효과 (Arulselvan et al, 2012), 항 산화 활성과 tyrosinase 및 elastase 저해 효과 (Jia et al, 2015), 고지 방식이 유도 비만 쥐에서 비만 방지 활성 (Sung et al, 2011)…”

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Evaluation of Physiological Activity of Traditional Welsh Onion (Allium fistulosum L.)

Lee,

Kim

2023

Asian J Beauty Cosmetol

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Purpose: This study was conducted to evaluate physiological activities, such as antioxidant activity and enzyme activity, of hot water extract of the four parts (flower, leaf and pseudostem, stem, and root) of traditional Welsh onion (Allium fistulosum L.) and then to provide basic data on traditional Welsh onion to support future research.Methods: Four parts of traditional Welsh onion plant were extracted with water heated at 80℃. Antioxidative and enzymatic activities, such as total polyphenol content, total flavonoid content, 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity, 2,2'-azino-bis-3-ethylbenzothiazoline–6-sulfonic acid (ABTS) radical scavenging activity, and the inhibitory activity on α-glucosidase, tyrosinase, and elastase enzymes, were measured.Results: Out of the hot water extract of the different parts, Allium fistulosum flower (AFF) extract had the highest content of antioxidants. In the Allium fistulosum leaf and pseudostem (AFLP), Allium fistulosum stem (AFS), and Allium fistulosum root (AFR) extracts, the total polyphenol content and DPPH radical scavenging activity of the root were high, and AFS had high total flavonoid content and ABTS radical scavenging activity. Regarding enzyme activity, α-glucosidase and elastase inhibitory activities were the highest in AFR, and tyrosinase inhibitory activity was the highest in AFS.Conclusion: We confirmed the physiological activity of the hot water extract of four parts of traditional Welsh onion. Our findings provide basic data for research into traditional Welsh onion, and can facilitate its future development as a functional material.

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Evaluation of Physiological Activity of Traditional Welsh Onion (Allium fistulosum L.)

Lee,

Kim

2023

Asian J Beauty Cosmetol

View full text Add to dashboard Cite

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Protective Effects of Welsh Onion (Allium fistulosum L.) on Drug-induced Hepatotoxicity in Rats

Cited by 1 publication

References 11 publications

Evaluation of Physiological Activity of Traditional Welsh Onion (Allium fistulosum L.)

Evaluation of Physiological Activity of Traditional Welsh Onion (Allium fistulosum L.)

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