Protective effects of imeglimin on the development of atherosclerosis in ApoE KO mice treated with STZ
Junpei Sanada,
Tomohiko Kimura,
Masashi Shimoda
et al.
Abstract:Background
Imeglimin is a new anti-diabetic drug which promotes insulin secretion from pancreatic β-cells and reduces insulin resistance in insulin target tissues. However, there have been no reports examining the possible anti-atherosclerotic effects of imeglimin. In this study, we investigated the possible anti-atherosclerotic effects of imeglimin using atherosclerosis model ApoE KO mice treated with streptozotocin (STZ).
Methods
ApoE KO mice wer… Show more
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