Abstract:Background
Chronic kidney disease (CKD) is the condition where the kidneys are unable to filter and clean the blood of waste properly. Hypertension, obesity, and diabetes are the leading risk factors for developing CKD. Fibrosis is regarded as a final common pathway leading to CKD. Sodium‐glucose co‐transporter 2 (SGLT‐2) inhibitors have shown to be renoprotective in type 2 diabetes patients. However, the mechanisms that underlie the renoprotective effects of SGLT‐2 inhibitors are unclear. Our study investigat… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.