Abstract:This study aims to evaluate the effect of diclofenac addition to the preservation solution Celsior on liver graft preservation.
Liver from Wistar rats were cold flushed in situ, harvested and then stored in Celsior solution (24h, 4°C) supplemented or not with 50 mg/L of diclofenac sodium salt. Reperfusion was performed (120 min, 37°C) using the isolated perfusion rat liver model. Perfusate samples were collected to evaluate transaminases activities after cold storage and by the end of reperfusion. In or… Show more
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