Protective effects of black tea-TV 25 on the cognitive impairments and some peripheral immune responses in intracerebroventricular colchicine injected rats

Sil, Susmita; Bhandari, Kaushik; Gupta, Pritha; Ghosh, Rupsa; Mitra, Analava; Ghosh, B. N.; Ghosh, Tusharkanti

doi:10.1007/s13596-017-0296-4

Cited by 1 publication

(1 citation statement)

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“…In addition, treatment with 5-(3 , S -dihydroxyphenyl)-γ-valerolactone (10 mg/kg BW), the major metabolite of EGCG, not only increased the activity of CD4 + T-cells but also enhanced the cytotoxic activity of natural killer (NK) cells [100]. Moreover, black tea (10.48 mg solid content/kg BW) showed a protective effect on the peripheral immune responses in rats injected with intracerebroventricular colchicine, regarding higher phagocytic activity of the white blood cells and the splenic polymorphonuclear cells, and higher cytotoxicity and lower leukocyte adhesion inhibition index of the splenic mononuclear cells [101]. Furthermore, Ahmed et al demonstrated that green tea by-products (contain 9.22% moisture, 20.1% crude protein, 2.91% crude fat, 18.2% crude fiber, 4.88% crude ash, 33.2% nitrogen-free extract, and 11.6% catechins) supplemented at the ratio of 0.5%, 1.0%, or 2.0% in diet positively modulated the proliferation of immune cells in goats in a linear mode [102].…”

Section: Immuno-regulative Activity In Vivomentioning

confidence: 99%

Health Functions and Related Molecular Mechanisms of Tea Components: An Update Review

Tang

Meng

Gan

et al. 2019

IJMS

255

150

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Tea is widely consumed all over the world. Generally, tea is divided into six categories: White, green, yellow, oolong, black, and dark teas, based on the fermentation degree. Tea contains abundant phytochemicals, such as polyphenols, pigments, polysaccharides, alkaloids, free amino acids, and saponins. However, the bioavailability of tea phytochemicals is relatively low. Thus, some novel technologies like nanotechnology have been developed to improve the bioavailability of tea bioactive components and consequently enhance the bioactivity. So far, many studies have demonstrated that tea shows various health functions, such as antioxidant, anti-inflammatory, immuno-regulatory, anticancer, cardiovascular-protective, anti-diabetic, anti-obesity, and hepato-protective effects. Moreover, it is also considered that drinking tea is safe to humans, since reports about the severe adverse effects of tea consumption are rare. In order to provide a better understanding of tea and its health potential, this review summarizes and discusses recent literature on the bioactive components, bioavailability, health functions, and safety issues of tea, with special attention paid to the related molecular mechanisms of tea health functions.

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Section: Immuno-regulative Activity In Vivomentioning

confidence: 99%