Protective Effect of the Intracellular Content from Potential Probiotic Bacteria against Oxidative Damage Induced by Acrylamide in Human Erythrocytes

Cuevas-González, Paúl F; Aguilar-Toalá, José E.; Garcı́a, Hugo S.; González-Córdova, A.F.; Vallejo-Córdoba, Belinda; Hérnández-Mendoza, Adrian

doi:10.1007/s12602-020-09636-9

Cited by 33 publications

(9 citation statements)

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“…Several studies described the antioxidant activities of IEs of different lactobacilli strains related to the enzyme superoxide dismutase (Masodsai et al), glutathione peroxidase (GPx) and glutathione (Amaretti et al, 2013;Wang et al, 2017). However, other metabolites such as proteinaceous compounds and fatty acids mixture may also contribute to the antioxidant capacity of intracellular content of specific probiotic strains (Aguilar-Toalá et al, 2019;Aguilar-Toala et al, 2020;Cuevas-Gonzalez et al, 2020).…”

Section: Discussionmentioning

confidence: 99%

Probiotic lactobacilli attenuate oxysterols-induced alteration of intestinal epithelial cell monolayer permeability: Focus on tight junction modulation

Casula

Pisano

Serreli

et al. 2023

Food and Chemical Toxicology

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Section: Discussionmentioning

confidence: 99%

Probiotic lactobacilli attenuate oxysterols-induced alteration of intestinal epithelial cell monolayer permeability: Focus on tight junction modulation

Casula

Pisano

Serreli

et al. 2023

Food and Chemical Toxicology

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“…Postbiotics in the food undergo no post-propagation treatment and contain only soluble factors, such as products or metabolic by-products secreted into the medium during bacterial growth [ 34 ]. However, in some work, bacterial cells are subjected to lysis after propagation by cell fragmentation techniques, including thermal, enzymatic, chemical, sonication, hyperbaric, solvent extraction, or a combination [ 36 , 38 , 39 ]. These treatments introduce many additional intracellular metabolites and cell wall-derived materials into the postbiotic mixture and impart new functions to the obtained postbiotics.…”

Section: Production and Classification Of Postbiotic Componentsmentioning

confidence: 99%

The Current and Future Perspectives of Postbiotics

Liang

Xing

2023

Probiotics & Antimicro. Prot.

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With the emphasis on intestinal health, probiotics have exploded into a vast market potential. However, new scientific evidence points out that the beneficial health benefits of probiotics are not necessarily directly related to viable bacteria. However, the metabolites or bacterial components of the live bacteria are the driving force behind health promotion. Therefore, scientists gradually noticed that the beneficial effects of probiotics are based on bacteria itself, metabolites, or cell lysates, and these factors are officially named “postbiotics” by the ISAPP. Postbiotic components are diverse and outperform live probiotics in terms of technology, safety, and cost due to their good absorption, metabolism, and organismal distribution. Postbiotics have been shown to have bioactivities such as antimicrobial, antioxidant, anti-inflammatory, anti-proliferative, and immunomodulation. Moreover, numerous studies have revealed the significant potential of postbiotics for disease treatment. This paper first presents the production and classification of postbiotics with examples from lactic acid bacteria (LAB), followed by the mechanisms of action with the most recent pre-clinical and clinical studies and the wide range of non-clinical and clinical applications of postbiotics. Furthermore, the current and future prospects of the postbiotic market with commercial available products are discussed. Finally, we comment on the knowledge gaps and future clinical applications with several examples.

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“…When ingested doses are higher than recommended (100 mg/kg), it can cause acute toxic effects and lethal effects when it exceeds 150 mg/kg [ 49 ]. Probiotic capacity to reduce the damage produced by acrylamide ingestion is associated with their antioxidant activity [ 52 ].…”

Section: Food Contaminants and Their Impact On Human Healthmentioning

confidence: 99%

Biodetoxification and Protective Properties of Probiotics

2022

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Probiotic consumption is recognized as being generally safe and correlates with multiple and valuable health benefits. However, the mechanism by which it helps detoxify the body and its anti-carcinogenic and antimutagenic potential is less discussed. A widely known fact is that globalization and mass food production/cultivation make it impossible to keep all possible risks under control. Scientists associate the multitude of diseases in the days when we live with these risks that threaten the population’s safety in terms of food. This review aims to explore whether the use of probiotics may be a safe, economically viable, and versatile tool in biodetoxification despite the numerous risks associated with food and the limited possibility to evaluate the contaminants. Based on scientific data, this paper focuses on the aspects mentioned above and demonstrates the probiotics’ possible risks, as well as their anti-carcinogenic and antimutagenic potential. After reviewing the probiotic capacity to react with pathogens, fungi infection, mycotoxins, acrylamide toxicity, benzopyrene, and heavy metals, we can conclude that the specific probiotic strain and probiotic combinations bring significant health outcomes. Furthermore, the biodetoxification maximization process can be performed using probiotic-bioactive compound association.

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Protective Effect of the Intracellular Content from Potential Probiotic Bacteria against Oxidative Damage Induced by Acrylamide in Human Erythrocytes

Cited by 33 publications

References 50 publications

Probiotic lactobacilli attenuate oxysterols-induced alteration of intestinal epithelial cell monolayer permeability: Focus on tight junction modulation

Probiotic lactobacilli attenuate oxysterols-induced alteration of intestinal epithelial cell monolayer permeability: Focus on tight junction modulation

The Current and Future Perspectives of Postbiotics

Biodetoxification and Protective Properties of Probiotics

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