1958
DOI: 10.3181/00379727-99-24429
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Protective Effect of Seaweed Extracts for Chicken Embryos Infected with Influenza B or Mumps Virus

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Cited by 140 publications
(56 citation statements)
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“…The potential antiviral activity of marine algal polysaccharides was first shown by Gerber, Dutcher, Adams, and Sherman (1958), who observed that the polysaccharides extracted from Gelidium cartilagenium (Rhodophyceae) protected the embryonic eggs against Influenza B or mump virus. The polysaccharides with antiviral activity were shown to be highly sulfated (Huheihel, Ishanu, Tal, & Arad, 2002).…”
Section: Antiviral Activitymentioning
confidence: 98%
“…The potential antiviral activity of marine algal polysaccharides was first shown by Gerber, Dutcher, Adams, and Sherman (1958), who observed that the polysaccharides extracted from Gelidium cartilagenium (Rhodophyceae) protected the embryonic eggs against Influenza B or mump virus. The polysaccharides with antiviral activity were shown to be highly sulfated (Huheihel, Ishanu, Tal, & Arad, 2002).…”
Section: Antiviral Activitymentioning
confidence: 98%
“…The original observations on antiviral activities of seaweed constituents go back more than 50 years to the observation that seaweed extracts protected chicken embryos against influenza B and mumps [141]. …”
Section: Bioactivity and Structure-activity Relationshipmentioning
confidence: 99%
“…An early report of the antimicrobial properties of seaweed extracts was published a decade later (Pratt et al, 1951), and several other papers appeared in the next two decades (Burkholder and Sharma, 1969). The antiviral e!ects of polysaccharides from marine algae toward mumps virus and in#uenza B virus were reported by Gerber et al (1958). Subsequently, polysaccharides fractions from extracts of red algae were found to inhibit herpes simplex virus (HSV) and other viruses (Burkholder and Sharma, 1969;Deig, 1974;Ehresmann et al, 1977;Richards et al, 1978).…”
Section: Introductionmentioning
confidence: 99%