Protective effect of Salvia hispanica (chia seeds) against obesity induced ovarian disorders in rat model

A review of the functional activities of chia seed and the mechanisms of action related to molecular targets

“…Moreover, the expression of the pro-inflammatory factor CD31 in the rat ovarian tissue was downregulated. 81 The <3 kDa peptide in the hydrolysates of CPI inhibits cholesterol synthesis by inhibiting the enzymatic reaction of 3-hydroxy-3-methylglutaryl–CoA reductase (HMG–COA) (the rate of the reaction decreased by 80.7%). 51…”