Protective Effect of Hedeoma drummondii against Formaldehyde-Induced Testicular Toxicity and Genotoxicity in Wistar Rats
Nadia Denys Betancourt-Martínez,
Pilar Carranza-Rosales,
Ezequiel Viveros-Valdez
et al.
Abstract:Formaldehyde (FA) is an oxidative stress inducer and a known carcinogen. Hedeoma drummondii has been shown to have potential as a chemopreventive agent. The aim of this study was to assess the protective effect of H. drummondii on FA-induced genotoxic damage, sperm quality parameters, and histological changes of the testis. The male Wistar rats used were divided into the following groups: (G1) 100 mg/kg H. drummondii; (G2) 10 mg/kg FA; (G3) 100 mg/kg H. drummondii + 10 mg/kg FA; (G4) phosphate-buffered saline;… Show more
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