2019
DOI: 10.5530/ijper.54.1.11
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Protective Effect of Capsaicin against Doxorubicin Induced Cardiotoxicity in Experimental Rats

Abstract: Aim: The aim of the present study was to evaluate the Cardioprotective effect of Capsaicin (CAP) against Doxorubicin (DOX) induced cardiotoxicity in experimental rats. Methods: The 24 wistar rats were randomly divided into four groups (with equal numbers): Normal-1% Dimethyl Sulfoxide (DMSO), DOX (15 mg/kg, i.p), CAP (10 mg/kg, p.o, alone) and CAP 10 mg/kg (in combination with DOX). Cardiotoxicity was induced in wistar rats by administering DOX with a cumulative dose of 15 mg/kg (i.p) for 2 weeks. CAP with a d… Show more

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Cited by 4 publications
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“…Syzygium cumini, commonly known as Jamun, Jaman, Black plum, Java plum or Jambul is a widely cultivated fruit tree with an annual production of 13.5 million tons (Verma et al, 2019). The Punjab and Sindh provinces of Pakistan have conducive climates for the production of S. cumini (Patel et al, 2010). It is grown on an area of 870 hectares in Pakistan with total production of 4811 tons (GOP, 2019).…”
Section: Introductionmentioning
confidence: 99%
“…Syzygium cumini, commonly known as Jamun, Jaman, Black plum, Java plum or Jambul is a widely cultivated fruit tree with an annual production of 13.5 million tons (Verma et al, 2019). The Punjab and Sindh provinces of Pakistan have conducive climates for the production of S. cumini (Patel et al, 2010). It is grown on an area of 870 hectares in Pakistan with total production of 4811 tons (GOP, 2019).…”
Section: Introductionmentioning
confidence: 99%