Protective effect of Calotropis procera latex extracts on experimentally induced gastric ulcers in rat

Bharti, Sudhakar; Wahane, V.D.; Kumar, Vijay

doi:10.1016/j.jep.2009.10.016

Cited by 57 publications

(38 citation statements)

References 30 publications

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“…In the present study, ME and aqueous solution of TGF-α and/or aprotinin were used on the healing of duodenal ulcer induced by acidified ASA. Previous studies have demonstrated that reactive oxygen specimens are involved in ASA induced gastric mucosal damage due to an enhancing effect of lipid peroxidation and attenuation of mucosal antioxidant mechanisms [30,31]. In the present study, ulcer index and MDA levels were significantly elevated in the duodenal tissue after intragastrically acidified ASA aplication ( Figure 1, Figure 2).…”

Section: Discussionsupporting

confidence: 61%

Effect of Oral TGF-Α Formulations on ASA Induced Duadenal Ulcer and The Role of Lipid Peroxidation in The Healing Process

Özer¹,

Gönül²,

Çelebi³

et al. 2012

Turk J Bioch

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Section: Discussionsupporting

confidence: 61%

Effect of Oral TGF-Α Formulations on ASA Induced Duadenal Ulcer and The Role of Lipid Peroxidation in The Healing Process

Özer¹,

Gönül²,

Çelebi³

et al. 2012

Turk J Bioch

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“…and served as peptic ulcer control group, Group III: received Famotidine (20 mg/kg/ day, p.o.) [17,18] and served as standard treatment group, Group IV: received ginger (100 mg/kg/day, p.o.) [16,19], and Group V: received marshmallow (100 mg/kg/day, p.o.)…”

Section: Experimental Designmentioning

confidence: 99%

Comparison between the Protective Effects of Famotidine, Ginger and Marshmallow on Pyloric Ligation-Induced Peptic Ulcer in Rats

Ss¹,

Ba²,

Aa³

et al. 2015

J Bioequiv Availab

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“…The root bark in the form of paste with rice vinegar is applied to elephantiasis of the legs and scrotum. It also acts as an emetic in doses of 30 to 60 g and has been used as a substitute for ipecacuanha [2][3][4][5][6][7][8][9] .…”

Section: Fig 1: Calotropis Proceramentioning

confidence: 99%

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2010

IJPSR

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Calotropis procera (Asclepiadaceae) is an erect, perennial shrub luxuriantly thriving in wastelands. It is commonly distributed in most parts of India and also distributed in Persia, tropical Africa and other tropical countries of the World. The aqueous extract of some parts have laxative property and beneficial in skin diseases, ulcers, enlargement of the spleen, abdominal glands, liver diseases, promotes digestive power and also useful in colics. The milky exudate is useful in skin diseases, tumour and ascitis. It is a very good purgative. Here an attempt has been taken to evaluate the antioxidant activity, CNS depressant activity and also antimicrobial activity of methanolic extract of fresh flowers of C. procera. In result, the methanolic flower extract showed a significant activity against DPPH free radicals and the IC 50 value is 64.87µg/ml. On the other hand, CNS depressant activity of the extract was also observed by using In Vivo model. In antimicrobial activity five different fungal species were inhibited by this extract and from the above study the flowers extract showed the maximum zone of inhibition against Candida parapsiliasis and the minimum against P. notatum ATCC 11625. Simultaneously, four different bacteria were inhibited in the concentration of 1mg/ml up to 4mg/ml flower extract of C. procera showing significant zone of inhibition against those.

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Protective effect of Calotropis procera latex extracts on experimentally induced gastric ulcers in rat

Cited by 57 publications

References 30 publications

Effect of Oral TGF-Α Formulations on ASA Induced Duadenal Ulcer and The Role of Lipid Peroxidation in The Healing Process

Effect of Oral TGF-Α Formulations on ASA Induced Duadenal Ulcer and The Role of Lipid Peroxidation in The Healing Process

Comparison between the Protective Effects of Famotidine, Ginger and Marshmallow on Pyloric Ligation-Induced Peptic Ulcer in Rats

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