Protection of cells from menadione-induced apoptosis by inhibition of lipid peroxidation

Effects of pentachlorophenol on the detoxification system in white-rumped munia ( Lonchura striata )

“…These findings accord with previous studies in which PCP exposed to hepatocytes induced ROS generation, increased lipid peroxidation production (MDA), and decreased levels of GSH (Dong et al, 2009). The depletion of GSH can result in an increase in ROS concentration, which may enhance lipid peroxidation intensity (Chiou et al, 2003). SOD enzymes represent the first line of cellular antioxidant protection against oxidative damage caused by ROS via converting O 2 − to O 2 and H 2 O 2 .…”

Tributyltin toxicity in abalone (Haliotis diversicolor supertexta) assessed by antioxidant enzyme activity, metabolic response, and histopathology

“…MDA, a product of lipid peroxidation, is a major contributor to the loss of cell function under oxidative stress [33]. The elevation of POD reflected an increase in ROS level, while a rise in ROS may increase lipid peroxidation, as measured by MDA intensity [34]. Combining previous results with the findings of this study, suggested that oxidative damage is one of the critical toxic mechanisms of TBT.…”

Trehalose protects wine yeast against oxidation under thermal stress

“…The samples were sonicated at 0°C for 80 periods of 3 s, with 3 s interval after each period. The extracts were used for detection of membrane lipid peroxidation through TBARS methodthiobarbituric acid reactive species (Herdeiro et al 2006;Chiou et al 2003).…”

“…A potential complication of lipid peroxide formation is probably the loss of membrane properties, which caused indiscriminate permeation of crucial or undesirable metabolites through this structure. Malondialdehyde, formed by the breakdown of polyunsaturated fatty acids, served as an index of the extent of lipid peroxidation (Chiou et al 2003). Thereafter, malondialdehyde was determined in cells directly exposed to heat stress, as well as, in cells adapted before being exposed to severe stress.…”