Protection of Cattle Against Lumpy Skin Disease

Capstick, P. B.; Coackley, W.

doi:10.1016/s0034-5288(18)34940-3

Cited by 32 publications

(17 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The clinical signs of natural and experimentally produced LSD have been well described (Thomas and Marè, 1945;Haig, 1957;Capstick and Coackley, 1961;Weiss, 1968;Prozesky and Barnard, 1982;Davies, 1991;Barnard et al, 1994). The course of the disease may be acute, subacute or chronic.…”

Section: Pathogenesis and Clinical Signsmentioning

confidence: 97%

“…Pregnant cows may abort and be in anoestrus for several months (Thomas and Marè, 1945;Alexander et al, 1957;Haig, 1957;Capstick and Coackley, 1961;Weiss, 1968;Prozesky and Barnard, 1982;Davies, 1991;Carn and Kitching, 1995b). The skin of the oedematous limbs may become necrotic and slough off, leaving deep ulcers, which may become secondarily infected with bacteria.…”

Section: Pathogenesis and Clinical Signsmentioning

confidence: 99%

“…It is possible to use the sheep pox/goat pox vaccine for cattle (Capstick and Coackley, 1961) but the cross-protection is not satisfactory and the use of this vaccine has been restricted to those countries where sheep and goat pox are endemic. The attenuated Neethling strain (LSDV) vaccine is used to vaccinate cattle in Africa.…”

Section: Vaccinesmentioning

confidence: 99%

“…Secondary bacterial infection or infestation by fly larvae may occur. Large nodules may become fibrotic and persist for several months; these are referred to as "sit fasts" (Thomas and Marè, 1945;Alexander et al, 1957;Haig, 1957;Capstick and Coackley, 1961;Weiss, 1968;Prozesky and Barnard, 1982;Davies, 1991;Carn and Kitching, 1995b). The scars may remain indefinitely, thus rendering the hide worthless (Green, 1959).…”

Section: Pathogenesis and Clinical Signsmentioning

confidence: 99%

See 3 more Smart Citations

Scientific Opinion on lumpy skin disease

2015

EFSA Journal

View full text Add to dashboard Cite

Lumpy skin disease (LSD) is a viral disease of cattle characterised by severe losses, especially in naive animals. LSD is endemic in many African and Asian countries, and it is rapidly spreading throughout the Middle East, including Turkey. LSD is transmitted by mechanical vectors, but direct/indirect transmission may occur. The disease would mainly be transferred to infection-free areas by transport of infected animals and vectors. In the EU, it could only happen through illegal transport of animals. The risk for that depends on the prevalence in the country of origin and the number of animals illegally moved. Based on a model to simulate LSD spread between farms, culling animals with generalised clinical signs seems to be sufficient to contain 90 % of epidemics around the initial site of incursion, but the remaining 10 % of simulated epidemics can spread up to 400 km from the site of introduction by six months after incursion. Whole-herd culling of infected farms substantially reduces the spread of LSD virus, and the more rapidly farms are detected and culled, the greater the magnitude of the reduction is. Only live attenuated vaccines against LSD are available. Homologous vaccines are more effective than sheep pox strain vaccines. The safety of the vaccines should be improved and the development of vaccines for differentiating between infected and vaccinated animals is recommended. Epidemics are not self-limiting when effective vaccination or culling are not applied. Active surveillance, rapid detection and prompt culling of infected herds are effective measures for LSD control. The role of vectors for LSD transmission should be further investigated in both controlled environments and the field. Awareness-raising campaigns for farmers and veterinary staff to promote recognition of LSD should be considered. The cooperation of the EU with neighbouring countries should be encouraged to prevent transboundary disease spread.

show abstract

Section: Pathogenesis and Clinical Signsmentioning

confidence: 97%

Section: Pathogenesis and Clinical Signsmentioning

confidence: 99%

Section: Vaccinesmentioning

confidence: 99%

Section: Pathogenesis and Clinical Signsmentioning

confidence: 99%

See 2 more Smart Citations

Scientific Opinion on lumpy skin disease

2015

EFSA Journal

View full text Add to dashboard Cite

show abstract

“…These viruses are responsible for some of the most economically significant diseases of domestic ruminants in Africa and Asia [9,10]. Live attenuated SPPV and subunit formulations have been used experimentally and in enzootic as well as outbreak areas as vaccines against sheeppox, goatpox, and lumpy skin disease [8,9]. …”

Section: Introductionmentioning

confidence: 99%

Modulation of macrophage functions by sheeppox virus provides clues to understand interaction of the virus with host immune system

Abuelsaad

Abdel‐Moneim

2005

Virol J

View full text Add to dashboard Cite

Background: Poxviruses encode a range of immunomodulatory genes to subvert or evade the challenges posed by the innate and adaptive immune responses. However, the inactivated poxviruses possessed immunostimulating capacity and were used as a prophylactic or metaphylactic application that efficiently reduced susceptibility to infectious diseases in different species. This fact is intensively studied in different genera of poxviruses. However, little is known about the basic mechanisms adopted by sheeppox virus (SPPV). SPPV causes an acute disease of sheep that recently, has been observed to reinfect its host in spite of vaccination.

show abstract