“…A series of critical articles, largely by the same two authors, and refuted by the PLATO investigators, have raised a multitude of concerns regarding the PLATO trial, including: worse outcome for US patients which were monitored by an independent organisation; higher rate of all‐cause death in clopidogrel‐treated patients compared to previous studies; obvious differences in the shape of the tablets which may have led to unblinded bias; and differences in the classification of diagnosis of MI …”