“…Likewise, proteasome activation through a triterpene, namely 18α-glycyrrhetinic acid (18α-GA), conferred resistance to Aβ-induced proteotoxicity in various AD nematode models, as well as to murine cortical neurons exogenously supplemented with enhanced concentrations of Aβ peptide [ 17 ]. Similar positive results have also been observed for other natural compounds in various AD models [ 24 , 25 ].…”