Protamine assisted rapid synthesis of carbon dots for living nucleolus imaging and gene delivery applications

Carbon dot composites for bioapplications: a review

“…In addition to antitumor drug delivery, there has also been significant interest in the application of CD composites for gene delivery. 301,302 Gene delivery is the process of introducing foreign DNA into host cells 303 and could be regarded as a special case of “drug” delivery. Gene delivery is one of the necessary steps required for gene therapy and genetic modifications.…”

“…For instance, in Yan and co-workers’ study, glyoxylic acid-modified CDs (GA-CDs) were used as a FRET ratiometric fluorescent probe for the detection of Cu 2+ in aqueous solution. 388 Similarly, Chen et al also applied cyclam-functionalized CDs as a FRET nanoprobe for the detection of Cu 2+ and S. 2–389 In addition to the above examples, the detection of other important metal ions such as Ag + , Cu 2+ , Cr 6+ , and Pb 2+ has also been successfully realized with CD composite-based sensing platforms. 390–401…”