Prostatorectal Fistula Associated with
            <sup>125</sup>
            Iodine Seed Radiotherapy

Mouli, K.; Sharifi, R.; Ray, Paul S.; Baumgartner, George; Guinan, Patrick

doi:10.1016/s0022-5347(17)52113-8

Journal of Urology

1983

DOI: 10.1016/s0022-5347(17)52113-8

|View full text |Cite

Prostatorectal Fistula Associated with ¹²⁵ Iodine Seed Radiotherapy

K. Mouli

R. Sharifi

Paul S. Ray

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

1986

1998

Publication Types

Select...

Article5

Relationship

Self Cite0

Independent5

Authors

Journals

Cited by 8 publications

(2 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Put to trial, the technique (avowed to deliver a higher dose to the prostate than could be administered safely by external beam irradiation and to improve theoretically local control) proved to be associated with unacceptable local control rates, attributed, at least in part, to inaccurate dose distribution by the freehand technique. The poor results led many to abandon brachytherapy as a treatment option for prostate carcinoma 5‐7…”

mentioning

confidence: 99%

“…The poor results led many to abandon brachytherapy as a treatment option for prostate carcinoma. [5][6][7] Then, during the 1980s several technologic advances took place. Based on the description by Watanabe et al of prostate ultrasound anatomy, Holm et al used transrectal ultrasound (TRUS) to guide percutaneous delivery of radioisotopes, achieving uniform seed distribution in the prostate.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Ten-year disease free survival after transperineal sonography-guided iodine-125 brachytherapy with or without 45-gray external beam irradiation in the treatment of patients with clinically localized, low to high gleason grade prostate carcinoma

Ragde

Elgamal

Snow³

et al. 1998

Cancer

318

View full text Add to dashboard Cite

BACKGROUND The authors report observed 10‐year brachytherapy results in the treatment of 152 consecutive patients with clinically organ‐confined prostate carcinoma. METHODS One hundred and fifty‐two consecutive patients with T1‐T3, low to high Gleason grade, prostate carcinoma were treated between January 1987 and June 1988 at Northwest Hospital in Seattle, Washington. Their median age was 70 years (range, 53‐92 years). Of these 152 patients, 98 (64%) received an iodine‐125 implant alone (Group 1), and the remaining 54 patients (36%), who were judged to have a higher risk of extraprostatic extension, also were treated with 45 gray (Gy) of external beam irradiation to the pelvis (Group 2). No patient underwent lymph node sampling, and none received androgen ablation therapy. Multivariate regression and the Mann‐Whitney rank sum test were used for statistical analysis. Preoperative patient data with associated success or failure outcomes at 10 years after treatment were used for training and validating a back‐propagation neural network prediction program. RESULTS The average preoperative prostate specific antigen (PSA) value, clinical stage, and Gleason grade were 11.0 ng/mL, T2, and 5, respectively. The median posttreatment follow‐up was 119 months (range, 3‐134 months). Overall survival 10 years after treatment was 65%. At last follow‐up only 3 of the 152 patients (2%) had died of prostate carcinoma. Ninety‐seven patients (64%) remained clinically and biochemically free of disease at 10 years of follow‐up and had an average PSA value of 0.18 ng/mL (range, 0.01‐0.5 ng/mL). In these patients a period of 42 months was required to reach the average PSA (0.5 ng/mL). The median to last PSA follow‐up was 95 months (range, 3‐134 months). Postoperative needle biopsies were negative in 56% of patients, positive in 15% of patients, and not available in 29% of patients. Only 6% of patients developed bone metastasis. At 10 years there was no statistically significant difference in treatment outcome between patients who received iodine‐125 alone, and those who received iodine‐125 with 45‐Gy external beam irradiation (P = 0.08). Nevertheless, in these two groups preoperative PSA, stage, and Gleason grade were significantly different (P < 0.01). In the artificial neural network analysis, pretreatment serum PSA was the most accurate predictor of disease‐free survival. CONCLUSIONS Percutaneous prostate brachytherapy is a valid and efficient option for treating patients with clinically organ‐confined, low to high Gleason grade, prostate carcinoma. Observed 10‐year follow‐up documents serum PSA levels superior to those reported in several published external beam irradiation series, and comparable to those published in a number of published radical prostatectomy series. Cancer 1998;83:989‐1001. © 1998 American Cancer Society.

show abstract

mentioning

confidence: 99%

mentioning

confidence: 99%

Ten-year disease free survival after transperineal sonography-guided iodine-125 brachytherapy with or without 45-gray external beam irradiation in the treatment of patients with clinically localized, low to high gleason grade prostate carcinoma

Ragde

Elgamal

Snow³

et al. 1998

Cancer

318

View full text Add to dashboard Cite

show abstract

New transurethral system for interstitial radiation of prostate cancer

Baumgartner

Callahan

McKiel

et al. 1988

Journal of Surgical Oncology

View full text Add to dashboard Cite

Direct endoscopic implantation of radioactive materials for carcinoma of the prostate without an open operation was accomplished by the use of modified existing transurethral instrumentation and techniques. The closed approach seems applicable particularly to the geriatric population, which is afflicted more commonly but is frequently not treated because of concurrent diseases or because the patient had transurethral resection of the prostate as a diagnostic procedure. Eleven patients were implanted using the transurethral route. Implantations were accomplished successfully with extremely low morbidity. Along with more conventional dosimetry studies, computer tomography was used to assess the placement of seeds. The direct visualization of the method suggests a potential for greater precision of seed placement as illustrated by computer tomography. In addition, this new instrumentation and method offers a low-risk procedure for carcinoma of the prostate that can be performed on an outpatient basis for selected patients.

show abstract

Use of fibrin sealant in the treatment of prostatic cutaneous fistula in a case of Pseudomonas prostatitis

Felipetto

Viganò

Cecchi

et al. 1995

International Urology and Nephrology

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Prostatorectal Fistula Associated with ¹²⁵ Iodine Seed Radiotherapy

Cited by 8 publications

References 3 publications

Ten-year disease free survival after transperineal sonography-guided iodine-125 brachytherapy with or without 45-gray external beam irradiation in the treatment of patients with clinically localized, low to high gleason grade prostate carcinoma

Ten-year disease free survival after transperineal sonography-guided iodine-125 brachytherapy with or without 45-gray external beam irradiation in the treatment of patients with clinically localized, low to high gleason grade prostate carcinoma

New transurethral system for interstitial radiation of prostate cancer

Use of fibrin sealant in the treatment of prostatic cutaneous fistula in a case of Pseudomonas prostatitis

Contact Info

Product

Resources

About

Prostatorectal Fistula Associated with 125 Iodine Seed Radiotherapy

Cited by 8 publications

References 3 publications

Ten-year disease free survival after transperineal sonography-guided iodine-125 brachytherapy with or without 45-gray external beam irradiation in the treatment of patients with clinically localized, low to high gleason grade prostate carcinoma

Ten-year disease free survival after transperineal sonography-guided iodine-125 brachytherapy with or without 45-gray external beam irradiation in the treatment of patients with clinically localized, low to high gleason grade prostate carcinoma

New transurethral system for interstitial radiation of prostate cancer

Use of fibrin sealant in the treatment of prostatic cutaneous fistula in a case of Pseudomonas prostatitis

Contact Info

Product

Resources

About

Prostatorectal Fistula Associated with ¹²⁵ Iodine Seed Radiotherapy