Prostatic Urethral Lift Improves Urinary Symptoms and Flow While Preserving Sexual Function for Men with Benign Prostatic Hyperplasia: A Systematic Review and Meta-analysis

Perera, Marlon; Roberts, Matthew J.; Doi, Suhail A.R.; Bolton, Damien

doi:10.1016/j.eururo.2014.10.031

Cited by 104 publications

(64 citation statements)

References 42 publications

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“…At the end of the 12th month, the total improvement in IPSS was 9.6 points. In a recent meta-analysis, IPSS was increased from 7.2 to 8.7 points following PUL [13]. Other studies have reported that PUL results in quick and constant relief of LUTSs with the improvement in symptom scores ranging from 41.8 to 50% [9,10,14,15,16,17,18].…”

Section: Discussionmentioning

confidence: 99%

“…According to the results of a recent meta-analysis, sexual health slightly improved after the PUL procedure, which was attributed to the discontinuation of LUTS and the related medical treatment [13]. …”

Section: Discussionmentioning

confidence: 99%

“…During a PUL procedure, permanent adjustable transprostatic UroLift implants can be placed to enlarge the urethral lumen and retract obstructive lateral lobes [11,12,13]. A total of 17 patients diagnosed with BPH who underwent UroLift® implantation between March 2011 and June 2015 were included in the study.…”

Section: Methodsmentioning

confidence: 99%

“…PUL has been reported to produce rapid results and significantly reduce LUTSs. In addition, compared with the surgical resection and ablation methods, the morbidity of PUL is lower and sexual functions are better preserved [8,9,10,11,12,13]. In a recent meta-analysis, the PUL procedure resulted in a 7.2-8.7 point increase in IPSS, 3.8-4.0 ml/s increase in the maximum flow rate and a 2.2-2.4 increase in the quality of life (QoL) with no sexual dysfunction being observed [13].…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Prostatic Urethral Lift: A New Minimally Invasive Treatment for Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia

et al. 2015

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Introduction: Prostatic urethral lift (PUL) is a minimally invasive procedure for the treatment of lower urinary tract symptoms (LUTSs) secondary to benign prostatic hyperplasia (BPH). The PUL procedure involves the placement of implants that retract the obstructing prostate lobes. This procedure achieves quantifiable improvements in functional outcomes and quality of life (QoL), while preserving erectile and ejaculatory functions. Methods: Seventeen patients diagnosed with BPH who had undergone the UroLift® procedure between March 2011 and June 2015 were retrospectively evaluated. The parameters evaluated in the pre-operative, intra-operative and 1-year post-operative period were demographic data, and pre-operative, intra-operative and 1-year post-operative results were obtained from the International Prostate Symptom Score (IPSS), Uroflowmetry QoL index, International Index of Erectile Function (IIEF) and Male Sexual Health Questionnaire (MSHQ) for ejaculatory function (MSHQ-EjD). Results: The average improvements from baseline to 12 months after intervention were significant for the total IPSS 9.6. There was a 4.2-point increase in Qmax, a 0.9-point improvement in QoL and a 32% decrease in PVR. No statistically significant difference was found in the IIEF and MSHQ-EjD scores when the pre-operative and post-operative 3rd and 12th month scores were evaluated (p > 0.05). Conclusions: PUL offers rapid improvement in voiding and storage symptoms, QoL and flow rate that is durable to 12 months after intervention. PUL is a minimally invasive procedure that has the moderate effect in treating troublesome LUTS secondary to benign prostatic obstruction and preserving total sexual function.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Prostatic Urethral Lift: A New Minimally Invasive Treatment for Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia

et al. 2015

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“…Indeed, a systematic review and meta-analysis were performed, confirming the therapeutic potential of PUL [23]. In 2015, the prospective, randomized, multinational BPH6 study was performed, comparing treatment response of PUL vs. TURP in 80 patients using an objective outcome measure termed BPH6 [24].…”

Section: The Evidencementioning

confidence: 99%

Minimally Invasive Treatment for Male Lower Urinary Tract Symptoms: the Prostatic Urethral Lift

Magistro

Strittmatter

Herlemann

et al. 2016

Curr Bladder Dysfunct Rep

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Male lower urinary tract symptoms (LUTS) are one of the most common non-malignant conditions afflicting quality of life in aging men. Treatment modalities for bothersome LUTS consist of pharmacotherapeutic and surgical options. There is particular interest in the development of minimally invasive procedures showing good efficacy with a favorable safety profile. An innovative technique offering rapid and durable relief without compromising sexual function is in great demand. The prostatic urethral lift represents a promising minimally invasive approach for the relief of bladder outlet obstruction (BOO) with few adverse events. The principle includes the application of retracting implants under cystoscopic guidance to unobstruct encroaching lateral lobes of the prostate. Clinical trials have confirmed improvement in LUTS with preservation of sexual function. The prostatic urethral lift appears to be a promising addition to the current repertoire of minimally invasive treatments for the management of LUTS.

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Prostatic urethral lift for the treatment of lower urinary tract symptoms in men with benign prostatic hyperplasia

Jung

McCutcheon

Reddy

et al. 2017

Cochrane Database of Systematic Reviews

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Prostatic Urethral Lift Improves Urinary Symptoms and Flow While Preserving Sexual Function for Men with Benign Prostatic Hyperplasia: A Systematic Review and Meta-analysis

Cited by 104 publications

References 42 publications

Prostatic Urethral Lift: A New Minimally Invasive Treatment for Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia

Prostatic Urethral Lift: A New Minimally Invasive Treatment for Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia

Minimally Invasive Treatment for Male Lower Urinary Tract Symptoms: the Prostatic Urethral Lift

Prostatic urethral lift for the treatment of lower urinary tract symptoms in men with benign prostatic hyperplasia

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