Prostatic mucinous carcinoma

Elbadawi, Ahmad; Craig, William; Linke, Charles A.; Cooper, Robert

doi:10.1016/0090-4295(79)90392-3

Cited by 44 publications

(29 citation statements)

References 27 publications

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“…This diagnosis is established on tumours with more than 25% of the gland containing extracellular mucin (3). Otherwise tumours with a smaller volume of mucin should be termed as “prostatic adenocarcinoma with mucinous features”.…”

Section: Discussionmentioning

confidence: 99%

Radical exenteration surgery is curative in locally advance mucinous prostatic adenocarcinoma involving bladder and rectum

Koo

Lynn

Saxby

2010

Journal of Surgical Case Reports

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The management of mucinous prostatic adenocarcinoma include hormonal treatment, radiotherapy and radical prostatectomy with variable long-term outcome. We report a 59 year old man with advanced mucinous prostatic adenocarcinoma involving almost the entire bladder and had failed treatment with hormonal and radiotherapy, but subsequently underwent radical pelvic exenteration surgery that resulted in long-term cure. He remains alive, his PSA remains undetectable and his surveillance CT scans did not show any evidence of recurrence after 11 years post-surgery. The favourable outcome of radical surgery suggests that radical surgery should be considered, especially in cases with failed initial treatments.

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Section: Discussionmentioning

confidence: 99%

Radical exenteration surgery is curative in locally advance mucinous prostatic adenocarcinoma involving bladder and rectum

Koo

Lynn

Saxby

2010

Journal of Surgical Case Reports

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“…1 The diagnosis of MACP relies on extraluminal pools of mucin found in more than 25% in prostatic tissue. 2 The mean age at the time of diagnosis is usually less than 60 years old. In overall the pre-treatment PSA levels are between 4.0 and 10.0 ng/mL and TNM is T1c, T2a or T2b.…”

Section: Discussionmentioning

confidence: 99%

“…1 Because 60 to 90% of PCa also secrete mucus, the diagnosis of primary MACP relies on the previously reported histologic criteria. 2 The defining criteria for this tumor were based on the presence>25% of mucinous component of the tumor. 3,4 MACP is associated with increased levels of prostate-specific antigen (PSA), metastatic spread to bones and responds to hormonal therapy.…”

Section: Introductionmentioning

confidence: 99%

Mucinous adenocarcinoma of the prostate: case report and review of the literature

Otsetov¹,

Kalchev²,

Takova³

et al. 2018

ICPJL

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“…Themechanismsunderlyingprostatecancerwithmetastasistotheomentumbutwithoutskeletalmetastasishaveyetto beelucidated.Itshouldbestatedthatourpatientdeveloped metastases only when the disease became unresponsive to hormonaltherapy.Thismightindicatethattheintroductionof androgenblockadeearlyoninthecourseofthediseasemay leadtochangingmetastaticpatterns.Itwouldappearthathistologicaltypesofprostatecancermaybehavedifferentlybiologicallyaccordingtothesitesofmetastasis.Additionally,the mucinous (mucin-secreting) adenocarcinoma of the prostate isreportedtobecharacterizedbyrarityofbonemetastases, limitedresponsetolocalradiationtherapy,andalackofhormonedependence [7,13].InthestudyperformedbyKehinde etal. [7],thepatientfulfilledthediagnosticcriteriaofmucinous(mucin-secreting)adenocarcinomaoftheprostate,given thatmorethan25%ofthetransurethralresectionofthepros-tate (TURP) chips contained lakes of mucin.…”

Section: Discussionmentioning

confidence: 99%

Prostate Cancer with Metastasis to the Omentum and Massive Ascites: A Rare Manifestation of a Common Disease

et al. 2009

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Background: The most common sites of metastasis in prostate cancer include bone and regional lymph nodes followed by lung, liver, and brain. Peritoneal metastasis without skeletal involvement is extremely rare. Case Report: We present herein a patient with hormone refractory prostate cancer with peritoneal metastasis accompanied by ascites but without bone metastasis. The patient initially experienced an excellent response to docetaxelbased chemotherapy. Conclusions: Prostate cancer can present with distant metastasis in unexpected sites. The lack of skeletal involvement does not exclude the possibility of distant metastases. The presence of ascites may indicate peritoneal disease which could be responsive to current standard chemotherapy.

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Prostatic mucinous carcinoma

Cited by 44 publications

References 27 publications

Radical exenteration surgery is curative in locally advance mucinous prostatic adenocarcinoma involving bladder and rectum

Radical exenteration surgery is curative in locally advance mucinous prostatic adenocarcinoma involving bladder and rectum

Mucinous adenocarcinoma of the prostate: case report and review of the literature

Prostate Cancer with Metastasis to the Omentum and Massive Ascites: A Rare Manifestation of a Common Disease

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