Prostatectomy Trends in the Bristol Area

Ball, Andrew J.; Powell, P. H.

doi:10.1111/j.1464-410x.1982.tb13585.x

Cited by 4 publications

(3 citation statements)

References 7 publications

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“…Transurethral resection of the prostate is a common operation and post-operative urinary tract infections contribute to morbidity and mortality (Ball and Powell, 1982;Murphy et al, 1984). Few British urologists, however, routinely employ antibiotic cover for this procedure (Wilson and Lewi, 1985).…”

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confidence: 99%

Single Dose, Oral Antibiotic Cover for Transurethral Prostatectomy

Shearman

Silverman

Johnson

et al. 1988

British Journal of Urology

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A double-blind, randomised, placebo-controlled study was carried out to determine the incidence and significance of bacteriuria in 110 patients undergoing transurethral resection of the prostate (TURP) and to assess the effect of a single pre-operative dose of Ciprofloxacin, a 4-quinolone antibiotic. Fifteen (68%) of the 22 patients in the placebo group with a positive post-operative urine culture subsequently developed a clinically apparent urinary tract infection (UTI) or received antibiotics in view of a positive urine culture. Adequate prostatic concentrations of Ciprofloxacin were achieved in all who received the drug. A significant reduction in the number of positive post-operative urine cultures and urinary tract infections requiring antibiotic therapy was achieved in this group. Six patients (5.5%) developed clinical evidence of septicaemia, 5 of whom were in the placebo group. No organisms resistant to Ciprofloxacin were encountered. Prior to surgery, 19% of all patients were found to have previously unsuspected bacteriuria. Ciprofloxacin tended to reduce the chances of this group developing a UTI or requiring antibiotics. Further, there was a highly significant reduction in post-operative infective complications in those with sterile urine at the time of resection who had received the drug. This study suggests that antibiotic cover for TURP is of clinical benefit. Ciprofloxacin may prove suited to this purpose, although further experience with the drug is still required.

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confidence: 99%

Single Dose, Oral Antibiotic Cover for Transurethral Prostatectomy

Shearman

Silverman

Johnson

et al. 1988

British Journal of Urology

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“…Many studies (Ball and Powell, 1982;Cafferkey et al, 1982;Hargreave et al, 1982;Millar et al, 1987) have shown a significant risk of bacterial infection following endoscopic manipulation of the urinary tract. It has been suggested that this morbidity can be reduced by the administration of antibiotics just prior to endoscopic surgery (Shah et al, 1981; No Murdoch and Badenoch, 1987;Shearman et al, 1988) (Table 5).…”

Section: Discussionmentioning

confidence: 99%

Norfloxacin Prophylaxis for Endoscopic Urological Surgery

Cutajar

1992

British Journal of Urology

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A series of 140 patients, undergoing various types of urological endoscopic procedures, was divided into 2 equal, parallel, randomised groups. The first group of 70 patients, undergoing lower urinary tract surgery, was randomised, half to receive norfloxacin prophylaxis and half no antibiotic cover; the other 70 patients, undergoing percutaneous renal surgery, were randomised, half to receive norfloxacin and half cefuroxime. It was found that 26% of patients not receiving antibiotic prophylaxis and 11% on cefuroxime prophylaxis developed post-operative bacteriuria, with a high incidence of urinary tract infection (UTI). Only 1 patient of 70 on norfloxacin prophylaxis developed post-operative bacteriuria, which quickly responded to prolongation of norfloxacin therapy. Prior to surgery, 10% of all patients were found to have previously undetected bacteriuria. This group was at high risk of developing post-operative infection. Norfloxacin effectively prevented post-operative bacteriuria and urinary tract infection in these patients. This study suggests that norfloxacin is a safe and effective prophylactic antibiotic in all forms of urological endoscopic procedures.

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“…Number of anaesthetics 0 < 6 6 1 1 [12][13][14][15][16][17] Total Greater than 50 number of cases is certainly insufficient to provide the training necessary for junior staff to be able to give anaesthetics unsupervised to this age group. Ideally, all these children should be anaesthetised by one of a small group of consultants (those who had the most extensive training in paediatric anaesthesia) thus giving them the greatest opportunity to maintain their skills.…”

Section: Number Of Months In Trainingmentioning

confidence: 99%

Anaesthesia for patients over 90 years of age. Outcomes after regional and general anaesthetic techniques for two common surgical procedures

et al. 1989

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SummaryPeri-operative morbidity and mortality and long term outcome of patients over 90 years of age who underwent either total hip arthroplasty or transurethral prostate resection were studied retrospectively. The outcomes of patients who received regional or general anaesthesia were compared. One hundred and forty-one patients underwent total hip arthroplasty and 44 patients underwent transurethralprostate resection during the study period (1975)(1976)(1977)(1978)(1979)(1980)(1981)(1982)(1983)(1984)(1985). Overall in-hospital mortality was 4.9%. Mortality at 30 days was 5.3% in patients who underwent hip arthroplasty during regional anaesthesia, compared with 6.8% in those who received general anaesthesia. Long term survival was similar for these two groups and was longer than projected for age and Correspondence should be addressed to Dr M. A. Warner, please. Accepted 20 July 1988. Forum 143gender-matched general population cohorts. The 30-day mortality rate was 3.2% for patients who underwent prostatic resection under regional anaesthesia; no deaths occurred in the general anaesthesia group. This difference was not statistically significant. Long term survival was similar for patients in both groups and was better than predicted. Anaesthetic technique did not influence short term morbidity and mortality or long term outcome for these procedures.

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Prostatectomy Trends in the Bristol Area

Cited by 4 publications

References 7 publications

Single Dose, Oral Antibiotic Cover for Transurethral Prostatectomy

Single Dose, Oral Antibiotic Cover for Transurethral Prostatectomy

Norfloxacin Prophylaxis for Endoscopic Urological Surgery

Anaesthesia for patients over 90 years of age. Outcomes after regional and general anaesthetic techniques for two common surgical procedures

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