Prostate Cancer: Incremental Value of Endorectal MR Imaging Findings for Prediction of Extracapsular Extension

Wang, Liang; Mullerad, Michael; Chen, Hui Ni; Eberhardt, Steven C.; Kattan, Michael W.; Scardino, Peter T.; Hricak, Hedvig

doi:10.1148/radiol.2321031086

Cited by 193 publications

(130 citation statements)

References 39 publications

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“…The availability of intraoperative TRUS is limited for most urologists. Nevertheless, preoperative TRUS can provide information on tumour location and possible ECE [15].…”

Section: Discussionmentioning

confidence: 99%

Are prostate needle biopsies predictive of the laterality of significant cancer and positive surgical margins?

et al. 2009

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analyses were used to determine which factors before and during LRP influenced the positive surgical margin status. RESULTSThere was only minor agreement between the laterality of positive needle biopsies and laterality of any cancer and significant cancer on final-specimen pathology ( κ = 0.135 and 0.151, respectively). This was irrespective of the number of needle cores obtained or final-specimen Gleason grade. Similarly, the laterality of dominant cancer on needle biopsy had only a minor agreement with the location of positive surgical margins ( κ = 0.050) and fair agreement with the location of extracapsular extension on final-specimen pathology ( κ = 0.235).

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“…The availability of intraoperative TRUS is limited for most urologists. Nevertheless, preoperative TRUS can provide information on tumour location and possible ECE [15].…”

Section: Discussionmentioning

confidence: 99%

Are prostate needle biopsies predictive of the laterality of significant cancer and positive surgical margins?

et al. 2009

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show abstract

“…MRI provides incremental value to clinical findings in staging patients of intermediate risk. For example, organ-confined disease implies that the patient may benefit from local therapy such as surgery [3]. In cases where there is discordance between PSA levels and biopsy findings (e.g.…”

Section: Clinical Application Of Mri In Localised Prostate Cancermentioning

confidence: 99%

Diffusion weighted imaging in prostate cancer

2010

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Diffusion-weighted imaging has generated substantial interest in the hope that it can be developed into a robust technique to improve the accuracy of MRI for the evaluation of prostate cancer. This technique has the advantages of short acquisition times, no need for intravenous administration of contrast medium, and the ability to study diffusion of water molecules that indirectly reflects tissue cellularity. In this article, we review the existing literature on the utility of DWI in tumour detection, localisation, treatment response, limitations of the technique, how it compares with other imaging techniques, technical considerations and future directions.

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“…With the implementation of diffusion-weighted and contrast-enhanced prostate MRI, the ability to spatially localize dominant lesions has reduced the risk of understaging and even been proposed as a criteria to omit biopsy in prostate cancer patients on active surveillance [17][18][19][20][21]. However, many significant prostate cancers detected on random biopsies fail to reveal a targetable lesion on MRI when compared to radical prostatectomy specimens [22].…”

Section: Editorialmentioning

confidence: 99%

Early detection of prostate cancer: can we have our cake and eat it too?

Masterson

Cary

Liu

2016

Expert Review of Anticancer Therapy

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Prostate Cancer: Incremental Value of Endorectal MR Imaging Findings for Prediction of Extracapsular Extension

Abstract: A model containing endorectal MR imaging findings has a significantly larger area under the ROC curve than a model containing only clinical variables; thus, endorectal MR imaging findings add incremental value in the prediction of ECE.

Cited by 193 publications

References 39 publications

Are prostate needle biopsies predictive of the laterality of significant cancer and positive surgical margins?

Are prostate needle biopsies predictive of the laterality of significant cancer and positive surgical margins?

Diffusion weighted imaging in prostate cancer

Early detection of prostate cancer: can we have our cake and eat it too?

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