Prostate cancer burden in Central and South America

Sierra, Mónica S.; Soerjomataram, Isabelle; Forman, David

doi:10.1016/j.canep.2016.06.010

Cited by 39 publications

(60 citation statements)

References 60 publications

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“…Therefore, both Mexican Immigrants and Mexican Americans may benefit from high survival for cancers requiring treatment. Yet, compared to Mexican Immigrants, Mexican Americans have higher mortality, which may reflect a higher incidence of aggressive prostate cancers in this population, more similar to that seen in developed countries …”

Section: Discussionmentioning

confidence: 84%

“…However, given that prostate cancer incidence is highest among African‐descent populations, as well as most developed countries, even among NHW populations, it is possible that Mexican Immigrants carry a lower prostate cancer risk from Mexico. Parallel to this, prostate cancer survival, especially for non‐localized stages, is impacted by early detection and widespread availability of diagnostic scans for staging, as well as access to complex treatment involving surgery, hormone and radiotherapy; thus, survival is likely to be higher in the US than in Mexico . In fact, US Hispanics have been shown to have from prostate cancer survival similar to NHWs, 93% at 5 years .…”

Section: Discussionmentioning

confidence: 99%

“…The age groups were modified for liver cancer to accommodate the known high prevalence of Hepatitis C virus (HCV), a major cause of liver cancer in the birth cohort of 1946-1965 in the US 15 ; resulting groups for liver cancer were ages [35][36][37][38][39][40][41][42][43][44][45][46][47][48][49][50][51][52][53][54][55][56][57][58][59][60][61][62][63][64], and 65 and older. Additionally, for prostate cancer, due to the skewed mortality experience toward older Abbreviations: CI, confidence interval; CUP, cancers of unknown primary, NHL, non-Hodgkin's lymphoma.…”

Section: Methodsmentioning

confidence: 99%

“…Parallel to this, prostate cancer survival, especially for non-localized stages, is impacted by early detection and widespread availability of diagnostic scans for staging, as well as access to complex treatment involving surgery, hormone and radiotherapy; thus, survival is likely to be higher in the US than in Mexico. 53 In fact, US Hispanics have been shown to have from prostate cancer survival similar to NHWs, 93% at 5 years. 37 Therefore, both Mexican Immigrants and Mexican Americans may benefit from high survival for cancers requiring treatment.…”

Section: Cancer Epidemiologymentioning

confidence: 99%

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Migration from Mexico to the United States: A high‐speed cancer transition

Pinheiro

Callahan

Stern

et al. 2017

Intl Journal of Cancer

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Differences and similarities in cancer patterns between the country of Mexico and the United States’ Mexican population, 11% of the entire US population, have not been studied. Mortality data from 2008–2012 in Mexico and California were analyzed and compared for causes of cancer death among adult and pediatric populations, using standard techniques and negative binomial regression. A total of 380,227 cancer deaths from Mexico and California were included. Mexican Americans had 49% and 13% higher mortality than their counterparts in Mexico among males and females, respectively. For Mexican Immigrants in the US, overall cancer mortality was similar to Mexico, their country of birth, but all-cancers-combined rates mask wide variation by specific cancer site. The most extreme results were recorded when comparing Mexican Americans to Mexicans in Mexico: with mortality rate ratios ranging from 2.72 (95%CI: 2.44–3.03) for colorectal cancer in males to 0.28 (95%CI: 0.24–0.33) for cervical cancer in females. These findings further reinforce the preeminent role that the environment, in its multiple aspects, has on cancer. Overall, mortality from obesity and tobacco-related cancers was higher among Mexican origin populations in the US compared to Mexico, suggesting a higher risk for these cancers, while mortality from prostate, stomach, and especially cervical and pediatric cancers was markedly higher in Mexico. Among children, brain cancer and neuroblastoma patterns suggest an environmental role in the etiology of these malignancies as well. Partnered research between the US and Mexico for cancer studies is warranted.

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Section: Discussionmentioning

confidence: 84%

Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Cancer Epidemiologymentioning

confidence: 99%

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Migration from Mexico to the United States: A high‐speed cancer transition

Pinheiro

Callahan

Stern

et al. 2017

Intl Journal of Cancer

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“…Prostate cancer was one of the two leading causes of cancer deaths in males in Latin America, except in Chile, Argentina, Colombia and El Salvador where it ranked third. Mortality rates varied by four-fold, with the highest rates seen in Belize (28.9), Uruguay (21.8), and Cuba (24.1) and the lowest in Peru, Nicaragua, and El Salvador (rates between 6.8 and 9.7) [73]. Lung cancer incidence rates ranged from as high as 50.1 among males in Uruguay, to as low as 1.1 among females in El Salvador.…”

Section: Germline Cancer Predisposition In Latin Americamentioning

confidence: 99%

State of Art of Cancer Pharmacogenomics in Latin American Populations

López‐Cortés

Guerrero

Redal

et al. 2017

IJMS

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Over the past decades, several studies have shown that tumor-related somatic and germline alterations predicts tumor prognosis, drug response and toxicity. Latin American populations present a vast geno-phenotypic diversity due to the great interethnic and interracial mixing. This genetic flow leads to the appearance of complex characteristics that allow individuals to adapt to endemic environments, such as high altitude or extreme tropical weather. These genetic changes, most of them subtle and unexplored, could establish a mutational profile to develop new pharmacogenomic therapies specific for Latin American populations. In this review, we present the current status of research on somatic and germline alterations in Latin America compared to those found in Caucasian and Asian populations.

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Challenges and opportunities in prostate cancer surgery in South America: Insights into robot‐assisted radical prostatectomies—A perspective

Bharadwaj,

Wireko,

Adebusoye

et al. 2023

Health Science Reports

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Background and AimsProstate cancer imposes a significant health burden, particularly in South America with its high incidence and mortality rates. This article explores the emergence of robot‐assisted radical prostatectomy (RARP) as a potential solution in the region.MethodsThis study relies on a comprehensive review of relevant literature. The analysis highlights the advantages of RARP, identifies impediments to its implementation, and proposes strategies to overcome these barriers.ResultsRARP demonstrates notable benefits, including improved functional outcomes, reduced complications, and minimized incisions. However, the integration of RARP in South America is hindered by challenges such as regional disparities, financial limitations, and data gaps. Limited healthcare infrastructure and a scarcity of skilled professionals further compound the issues.ConclusionDespite its potential, RARP faces obstacles to widespread adoption in South America. Strategic solutions encompassing technology investment, healthcare infrastructure enhancement, and workforce training are imperative. Overcoming these challenges can establish RARP as a crucial tool in managing prostate cancer in the region, ultimately enhancing patient care and treatment outcomes.

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Prostate cancer burden in Central and South America

Cited by 39 publications

References 60 publications

Migration from Mexico to the United States: A high‐speed cancer transition

Migration from Mexico to the United States: A high‐speed cancer transition

State of Art of Cancer Pharmacogenomics in Latin American Populations

Challenges and opportunities in prostate cancer surgery in South America: Insights into robot‐assisted radical prostatectomies—A perspective

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