Prostate Brachytherapy Seed Reconstruction Using C-Arm Rotation Measurement and Motion Compensation

Dehghan, Ehsan; Lee, Junghoon; Moradi, Mehdi; Wen, Xu; Fichtinger, Gabor; Salcudean, Septimiu E.

doi:10.1007/978-3-642-15705-9_35

Cited by 7 publications

(10 citation statements)

References 8 publications

(18 reference statements)

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“…For reconstruction of the implant in fluoroscopy, we implemented and used the method described in [7]. The steps for acquiring the fluoroscopy reconstruction included C-arm pose estimation from rotation angle and compensation for sagging, followed by backprojection of the seeds, and finally seed to needle assignment using a minimum cost flow (MCF) algorithm.…”

Section: Methodsmentioning

confidence: 99%

“…In recent years, the fluoroscopy reconstruction problem has been extensively addressed. Given 3-5 fluoroscopy images, and the relative pose of the C-arm in each acquisition, the back-projection technique can be used to reconstruct the 3D implant [7]. For registration, attaching fiducial markers to the ultrasound probe [8], using the ultrasound probe itself as a fiducial [4], or using the seeds as fiducials [9] have been mentioned.…”

Section: Introductionmentioning

confidence: 99%

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Towards Intra-operative Prostate Brachytherapy Dosimetry Based on Partial Seed Localization in Ultrasound and Registration to C-arm Fluoroscopy

Moradi

Mahdavi

Lobo

et al. 2011

Lecture Notes in Computer Science

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Abstract. Intraoperative dosimetry during prostate brachytherapy is a long standing clinical problem. We propose a novel framework to address this problem by reliable detection of a subset of seeds from 3D transrectal ultrasound and registration to fluoroscopy. Seed detection in ultrasound is achieved through template matching in the RF ultrasound domain followed by thresholding and spatial filtering based on the fixed distance between stranded seeds. This subset of seeds is registered to the complete reconstruction of the implant in C-arm fluoroscopy. We report results, validated with a leave-one-needle-out approach, both in a phantom (average post-registration seed distance of 2.5 mm) and in three clinical patient datasets (average error: 3.9 mm over 113 seeds).

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Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Towards Intra-operative Prostate Brachytherapy Dosimetry Based on Partial Seed Localization in Ultrasound and Registration to C-arm Fluoroscopy

Moradi

Mahdavi

Lobo

et al. 2011

Lecture Notes in Computer Science

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“…The motion compensation algorithm can be combined with other seed matching algorithms, such as REDMAPS (Lee et al, 2011) as reported in Dehghan et al (2010). In comparison to XMARSHAL, REDMAPS provides the optimal matching solution.…”

Section: Tablementioning

confidence: 99%

“…Considering the simplicity of the implementation, high reconstruction accuracy and favorable computational speed, this algorithm is suitable for clinical translation. The underlying idea and limited preliminary data was presented at a recent conference (Dehghan et al, 2010). This manuscript provides a more detailed description of the methodology and performance analysis on 100 clinical data sets.…”

Section: Introductionmentioning

confidence: 99%

New Image-Based Techniques for Prostate Biopsy and Treatment

Moradi¹

2012

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Public reporting burden for this collection of information is estimated to average 1 hour per response, including the time for reviewing instructions, searching existing data sources, gathering and maintaining the data needed, and completing and reviewing this collection of information. Send comments regarding this burden estimate or any other aspect of this collection of information, including suggestions for reducing this burden to Department of Defense, Washington Headquarters Services, Directorate for Information Operations and Reports (0704-0188), 1215 Jefferson Davis Highway, Suite 1204, Arlington, VA 22202-4302. Respondents should be aware that notwithstanding any other provision of law, no person shall be subject to any penalty for failing to comply with a collection of information if it does not display a currently valid OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. REPORT DATE April 2012 REPORT TYPE Annual Summary DATES COVERED PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) 8. PERFORMING ORGANIZATION REPORT NUMBERUniversity of British Columbia Vancouver, CA V6T 1Z4 SPONSORING / MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR'S ACRONYM(S) U.S. Army Medical Research and Materiel Command Fort Detrick, Maryland 21702-5012 SPONSOR/MONITOR'S REPORT NUMBER(S) DISTRIBUTION / AVAILABILITY STATEMENTApproved for Public Release; Distribution Unlimited SUPPLEMENTARY NOTES ABSTRACTThis report details the research and training outcomes of a prostate cancer postdoctoral training award. The work resulted in technologies for segmentation, cancer detection, and brachytherapy seed detection that take advantage of ultrasound vibroelastography and ultrasound RF signals. In segmentation, we report a fully automatic algorithm that combines B-mode and elastography data within an active shape model approach. For cancer detection, we report the sensitivity of 75.5% for elastography in cancer detection. In brachytherapy seed detection and dosimetry, we showed that the use of raw RF ultrasound signals can result in partial detection of the seed clouds, sufficient for registration to C-arm fluoroscopy for the purpose of dosimetry. The results were published in form of five journal publications and six conference presentations in international journals and conferences. The PI attended nine conferences and meetings during the course of the award. SUBJECT TERMS IntroductionThis documents reports the accomplishments of the PI, Dr Mehdi Moradi, supported by the postdoctoral training Award W81XWH-10-1-0201, from April 1, 2010 to March 31, 2012. The progress on the specific task listed in the award will be listed. Since this is a training award, other achievements of the trainee during the award will be enumerated as well. The technology developed for vibroelastography was described in the annual report. We will focus on progress towards specific clinical outcomes and achievements of the trainee.The rationale of the proposal is that prostate tumors cannot be visualized in the ultrasound Bmode i...

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“…The latter seed positions are computed from intraoperative fluoroscopic data [6]. We extended the study to include the quantification of seed movement from the intra-operative conditions to immediately after surgery where CT reconstruction is used to compute seed positions [7].…”

Section: Introductionmentioning

confidence: 99%

Quantifying Stranded Implant Displacement Following Prostate Brachytherapy

Lobo

Moradi

Chng

et al. 2011

Lecture Notes in Computer Science

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Abstract. We aim to compute radioactive stranded-implant displacement during and after prostate brachytherapy. We present the methods used to identify corresponding seeds in planned, intra-operative and postimplant patient data that enable us to compute seed displacements. A minimum cost network flow algorithm is used, on 8 patients, for needle track detection to group seeds into needles that can be matched between datasets. An iterative best line detection algorithm is used both to help with needle detection and to register the different datasets. Our results show that there was an average seed misplacement of 5.08±2.35 mm during the procedure, which then moved another 3.10±1.91 mm by the time the quality assurance CT was taken. Several directional trends in different regions of the prostate were noted and commented on.

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Prostate Brachytherapy Seed Reconstruction Using C-Arm Rotation Measurement and Motion Compensation

Cited by 7 publications

References 8 publications

Towards Intra-operative Prostate Brachytherapy Dosimetry Based on Partial Seed Localization in Ultrasound and Registration to C-arm Fluoroscopy

Towards Intra-operative Prostate Brachytherapy Dosimetry Based on Partial Seed Localization in Ultrasound and Registration to C-arm Fluoroscopy

New Image-Based Techniques for Prostate Biopsy and Treatment

Quantifying Stranded Implant Displacement Following Prostate Brachytherapy

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