Prostate biopsy in the supine position in a standard 1.5-T scanner under real time MR-imaging control using a MR-compatible endorectal biopsy device

Abstract

Thirty-seven consecutive patients with elevated PSA levels and negative tumor prostate biopsies underwent a MR-guided prostate biopsy in a 1.5-T scanner in the supine position. After localization of suspected tumor areas using an endorectal coil and two body-phased array coils, the biopsy device was positioned without any repositioning of the patient. The biopsy device consisted of a mount, a ball joint, a positioning stage and an insertion stage with a needle guide, which was filled with a MR-visible fluid to control positioning of the needle using a balanced steady-state free precession sequence (TrueFISP) and a high-resolution turbo spin echo (T2-TSE) sequence. Core biopsies were taken manually in the magnet. The biopsy needle could be correctly positioned in all cases. Suspected lesions with a diameter > or =10 mm could be successfully punctured. Four to nine (mean = 6) biopsies were taken per patient. In 14 patients, prostate cancer was confirmed at histology. Twenty-four biopsies positive for cancer were performed in 14 patients. A correct correlation was found between the site of biopsy and histology. MR-guided prostate biopsy can be effective in increasing primary positive tumor biopsy results in patients with a history of negative tumor TRUS-guided prostate biopsies.

MR-guided biopsy of the prostate: correlation of cancer detection rate with number of previous negative TRUS biopsies

“…MRI-guided biopsy can be utilized as a primary or secondary rebiopsy technique because the available data imply that there are higher detection rates from one MRI-guided biopsy compared to TRUS-guided repeat biopsies, up to the third rebiopsy (4). Only four 1.5 T MRI-guided biopsy studies, with a total of 176 patients, have been previously published (19,28,30,31). The reported overall detection rates ranged between 42% and 55% with a high proportion of transition zone cancers, accounting for 35% of removed cores.…”

Direct Comparison of Targeted MRI-Guided Biopsy with Systematic Transrectal Ultrasound-Guided Biopsy in Patients with Previous Negative Prostate Biopsies

“…Currently, MRI of the prostate has the highest sensitivity with a fair specificity in detecting PC [4]. During the past 7 years, several groups have established targeted MRI-guided biopsies (MR-GB) and have reported cancer detection rates between 37 and 59% in the re-biopsy setting for patients with persisting suspicion for PC [5,6,7,8]. Meanwhile, more and more groups have implemented MR-GB into clinical routine.…”

Magnetic Resonance - Transrectal Ultrasound Fusion Guided Prostate Biopsy

“…Engelhard ve ark. (10) in-bore yöntem ile 37 hastalık bir grupta kanser saptama oranını %38 olarak saptamışlardır. Ayrıca 100 hastalık bir seride Roethke ve ark.…”