volume 51, issue 5, P584-590 2018
DOI: 10.1590/0037-8682-0235-2018
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Abstract: Introduction: The Mayaro virus (MAYV), which is an arbovirus closely related to the Chikungunya virus, causes a dengue-like acute illness that is endemic to Central and South America. We investigated the anti-MAYV activity of prostaglandin A 1 (PGA 1), a hormone which exhibits antiviral activity against both ribonucleic acid (RNA) and deoxyribonucleic acid (DNA) viruses. Further, we examined the effects of inducting the stress protein HSP70 following PGA 1 treatment. Methods: Hep-2 cells infected with MAYV wer…

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