Prostacyclin Reduces Incidence of Myocardial Damage After Coronary Endarterectomy

Successful emergency surgery for spontaneous coronary artery dissection in a young woman

“…At the time of rewarming prostaglandin PGI 2 (Prostacyclin) was initiated to achieve cytoprotective and antiaggregatory effects after coronary endarterectomy. 3 was uneventful, and she was remaining stabile on standard antiplatelet therapy.…”

Redo surgery after multiple coronary endarterectomy

“…In the past, the worldwide incidence of coronary endarterectomy ranged from 1.9% to 17.9%. 1,2 However, controversy in perioperative morbidity and mortality significantly decreased utilization of this method in many respectable cardiac centers. The same situation happened in our institution regardless of our experience and reputation in this field.…”

“…The anastomosis were closed without patching and grafts were routinely flushed with cold crystalloid cardioplegic solution to evaluate distal runoff. 2 Clinical outcome after the first surgery was good, and the patient was discharged from the hospital on the postoperative day #10, without complications.…”

“…1 High technical demands, long duration of the procedure, and consequent increased perioperative morbidity and mortality are arguments that discourage the use of coronary endarterectomy. 2 End-stage coronary artery disease is usually complicated with heart remodeling and functional mitral and tricuspid regurgitation. 3 In this report we present clinical findings and outcome in redo surgery 15 years after multiple coronary endarterectomies, complicated overtime with low ejection fraction (EF) and mitral and tricuspid insufficiency.…”

Systematic Reductive Annuloplasty of the Mitral and Tricuspid Valves in Patients With End-Stage Ischemic Dilated Cardiomyopathy

“…Cardioplegic arrest was used with standard cardiopulmonary bypass, and moderate systemic hypothermia (28 to 30°C). In most of the cases, especially in patients with pulmonary hypertension and/or CABG with endarterectomy, prostaglandin PGI 2 (Prostacyclin) was used to reduce pulmonary vascular resistance, and to achieve cytoprotective and antiaggregatory effects 10,11 . Transseptal approach to the mitral valve was used as a routine approach in all cases.…”