Prospects of using adaptive phage therapy in the rehabilitation of post-COVID-19 patients

Abstract

The work is devoted to the organization of postcovid rehabilitation by developing a strategy of adative phage therapy, which is the production and application of a complex of bacteriophages for a specific medical institution/department based on an up-to-date collection of hospital bacterial strains isolated from the biomaterial of patients of the same institution.
 Bacteriophages were actively used in the world in the 20-40s of the twentieth century in various fields of medicine, but the rapid development of phage resistance in each individual case limited their use. The use of complex preparations of bacteriophages from the collection pure lines of bacteriophages of the SPC "MikroMir" a set of various phages aimed at restoring the human microbiome after a covid infection allowed to sharply reduce the number of antibiotics used in intensive care units and reduce antibiotic resistance with proven safety of phage therapy.