Prospects for enhancement of targeted radionuclide therapy of cancer using ultrasound

Abstract

Ultrasound-mediated drug delivery is a promising means of enhancing delivery, distribution and effectiveness of drugs within tumours. In this review, prospects for exploiting ultrasound to improve the tumour delivery and distribution of radiolabelled antibodies for radioimmunotherapy and to overcome barriers imposed by tumour microenvironment are discussed.

Microbubble-Mediated Delivery for Cancer Therapy

“…These can be divided into the mechanical effects of acoustic cavitation and acoustic radiation force, and thermal effects. Reprinted by permission from John Wiley and Sons, Journal of Labelled Compounds and Radionuclides[28].…”