The Zhuxi ore deposit, located in Jiangxi province, South China, is the largest tungsten reserve in the world. To better understand the geological structure and distribution of orebodies, we conducted a high resolution three-dimensional P-wave velocity tomography of the uppermost 0.5 km beneath the Zhuxi ore deposit and adjacent area. Our velocity model was derived from 761,653 P-wave first arrivals from 998 control-source shots, recorded by a dense array. As the first 3D P-wave velocity structure of the Zhuxi ore deposit, our model agrees with local topographic and tectonic structures and shows depth-dependent velocity similar to laboratory measurements. The Carboniferous formations hosting the proven orebodies are imaged as high velocities. The high-velocity anomalies extend to a larger area beyond the proven orebodies, and the locations of high-low velocity boundaries are in accordance with the boundaries between the Neoproterozoic formation and the Carboniferous-Triassic formation. Seismic tomography reveals that high-velocity anomalies are closely related to the mineralized areas. Our results are helpful for further evaluating the total reserves and suggest that seismic tomography can be a useful tool for mineral exploration.Minerals 2020, 10, 148 2 of 18 activity [6,7]. The thrust nappe structure can cause interlaminar nappe slip of the ore-bearing stratum and form weak zones that are conducive to magma emplacement and orebody storage [8]. The Zhuxi ore deposit was formed after the multi-stage tectonic evolution of oblique intrusion of granitic magmas, skarn mineralization, hydrothermal cooling and alteration, and precipitation of metal sulfides [7]. The major orebodies beneath the Zhuxi ore deposit are located in the contacting zones between the Huanglong Formation and the Neoproterozoic slate (Figure 1), bounded by several NE-striking faults [1]. The ores are mostly hydrothermal-type copper-iron ores at shallow depths, whereas there are rich stratoid skarn scheelite (copper) ores at greater depths [7].Until now, the reserves and distribution of the Zhuxi ore deposit have been mainly evaluated from the geological survey [2] and borehole explorations [1,7]. Two major ore belts-the Main Ore Belt (MOB) and the North Ore Belt (NOB) (Figure 1)-have been identified. As revealed by borehole inspections, most orebodies are NE-trending and dominated by a veinlet-disseminated structure [7]. Due to the limited number of inspecting boreholes, however, some geological problems are not fully understood. Such as the stratigraphic boundaries between different formations, the spatial distribution of the orebodies outside the prospecting survey area, and the shape of the concealed orebodies at depth reconstructed by nappe structure. These limited understandings restrict the study and prospecting of metallogenic regularity in the Zhuxi ore deposit and adjacent area. Imaging the subsurface structure with geophysical methods is helpful in overcoming these plights.Recently, several geophysical explorations (e.g., gravity-magnet...