Prospective validation of the Glasgow Meningococcal Septicaemia Prognostic Score. Comparison with other scoring methods

Riordan, F. A. I.; Marzouk, O.; Thomson, A. P. J.; Sills, J. A.; Hart, C. A.

doi:10.1007/s00431-002-1024-7

Cited by 34 publications

(11 citation statements)

References 38 publications

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“…Children who have a Glasgow meningococcal septicaemia prognostic score of 8 or more out of 15 have an increased risk of death21; they should generally be transferred to a paediatric intensive care unit after elective intubation and placement of central line, arterial line, and catheter. Intermittent positive pressure ventilation, sedation, and restoration and maintenance of the central circulation are the mainstays of care in the paediatric intensive care unit.…”

Section: How Is Meningococcal Disease Managed?mentioning

confidence: 99%

Meningococcal disease and its management in children

Hart

Thomson

2006

BMJ

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Section: How Is Meningococcal Disease Managed?mentioning

confidence: 99%

Meningococcal disease and its management in children

Hart

Thomson

2006

BMJ

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“…Probably the scoring system that is most easily and commonly employed is the Glasgow Meningococcal Septicaemia Prognostic Score (GMSPS) ( Table 3) [31]. The predictive value of the GMSPS compares favorably with other proposed scoring systems [28,32].…”

Section: Severity Of Illness Scoring Systemsmentioning

confidence: 98%

Severe Meningococcal Infections in Children and Adolescents

Graham¹,

Goldstein²

2006

CPR

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Infection with Neisseria meningitidis remains one of the most devastating illnesses in pediatrics. Affected patients can progress from a mild viral-like illness to death within a matter of hours. Additionally, the definitive clinical diagnosis cannot be reached until the characteristic petechial rash appears, making differentiating meningococcal infection from a benign viral illness impossible. This review will discuss the epidemiology, bacteriology, pathophysiology, treatment, and potential new therapies for severe meningococcal infections in children and adolescents.

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“…[3][4][5] Existem scores de prognóstico, validados para doença meningocócica invasiva (DMI) que combinam dados clínicos e laboratoriais. Nestes estão incluídos o Glasgow Meningococcal Septicaemia Prognostic Score (GMSPS), 6 e scores genéricos para cuidados intensivos pediátri-cos como o Paediatric Risk of Mortality (PRISM) 7 e o Martins L, et al Doença meningocócica invasiva: aplicação do BEP score, Acta Med Port 2015 May-Jun;28(3):342-346…”

Section: 2unclassified

“…3 É importante ter em conta que alguns scores, como o PRISM ou o GMSPS, usam dados clínicos, estando dependentes de uma avaliação que é subjetiva em muitos aspetos, o que pode reduzir a sua fiabilidade. 3,6,7 Recentemente foi desenvolvido e validado um novo score prognóstico por um grupo de investigadores de vá-rios centros europeus de cuidados intensivos pediátricos, baseado na contagem plaquetar e no excesso de base, o BEP score (base excess and platelets). Este score é calculado pela fórmula:…”

Section: 2unclassified

Doença Meningocócica Invasiva: Aplicação do Base Excess and Platelets Score numa Unidade de Cuidados Intensivos Pediátricos Portuguesa

et al. 2015

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Introduction:Meningococcal infection has a high mortality and morbidity. Recently a new prognostic scoring system was developed for paediatric invasive meningococcal disease, based on platelet count and base excess -base excess and platelets score. The main objective of this study was to evaluate the accuracy of base excess and platelets score to predict mortality in children admitted to intensive care due to invasive meningococcal disease. Material and Methods: Observational study, with retrospective data collection, during a 13.5 years period (01/2000 to 06/2013). Mortality by invasive meningococcal disease and related factors (organ dysfunction and multi-organ failure) were analysed. The base excess and platelets score was calculated retrospectively, to evaluate its accuracy in predicting mortality and compared with Paediatric Risk of Mortality and Paediatric Index of Mortality 2 . Results: Were admitted 76 children with invasive meningococcal disease. The most frequent type of dysfunction was cardiovascular (92%), followed by hematologic (55%). Of the total, 47 patients (62%) had criteria for multi-organ failure. The global mortality was 16%. Neurologic and renal dysfunction showed the strongest association with mortality, adjusted odds ratio 315 ( Conclusions:The Base Excess and Platelets score may be useful tool in invasive meningococcal disease because is highly sensitive and specific and is objectively measurable and readily available at presentation.

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Prospective validation of the Glasgow Meningococcal Septicaemia Prognostic Score. Comparison with other scoring methods

Cited by 34 publications

References 38 publications

Meningococcal disease and its management in children

Meningococcal disease and its management in children

Severe Meningococcal Infections in Children and Adolescents

Doença Meningocócica Invasiva: Aplicação do Base Excess and Platelets Score numa Unidade de Cuidados Intensivos Pediátricos Portuguesa

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