Prospective swallowing outcomes after IMRT for oropharyngeal cancer: Dosimetric correlations in a population-based cohort

Factors associated with the availability of iodized salt at household level: a case study in Bangladesh

“…All statistical analyses were performed in R version 3.3.0. We used MCMCglmm package in R for Bayesian models, which has previously been applied in health-and nutrition-related studies (41)(42)(43) . The adjusted odds ratio of posterior mean (OR) in favour with its 95 % credible interval (CI) were computed for the coefficient of each of the covariates.…”

Long-term quality of life and psycho-social outcomes after oropharyngeal cancer surgery and radial forearm free-flap reconstruction: A GETTEC prospective multicentric study

“…This accounts for a modified oral diet being patients' main complaint in daily life. In a prospective study evaluating swallowing outcomes after intensity-modulated RT for OPC, Guo et al found a feeding tube dependence rate of 8.3% one year after therapy [16]. In a systematic review of functional outcomes after transoral robotic surgery, Hutcheson et al showed that long-term gastrostomy tube rates ranging from 0% to 7%, were reported by 12 studies in a total of 441 patients, and a mean follow-up in most studies between 1 and 2 years [17].…”

Helical intensity‐modulated radiotherapy with concurrent chemotherapy for oropharyngeal squamous cell carcinoma: A prospective investigation of acute swallowing and toxicity patterns

“…6,[8][9][10][11][12] Grade 3 mucositis during CRT for oropharyngeal SCC is common, with incidence rates ranging from 21%-80% reported in the literature. 6,7,10,[13][14][15] Oropharyngeal dysphagia is of particular concern for this patient group, 16,17 with aspiration pneumonia an underreported consequence of CRT for oropharyngeal SCC. 18,19 Oropharyngeal tumors are associated with greater difficulty in managing semisolid diets, 20 with one-third to two-thirds of patients experiencing grade 3 dysphagia requiring enteral nutrition support when undergoing CRT using intensity-modulated radiotherapy (IMRT).…”

“…2 Currently, chemoradiotherapy (CRT) is considered the standard of care for locally advanced oropharyngeal SCC, 3,4 offering 5-year survival rates of 74% for HPV-positive disease 5 with the benefit of organ function preservation. 6,7,10,[13][14][15] Oropharyngeal dysphagia is of particular concern for this patient group, 16,17 with aspiration pneumonia an underreported consequence of CRT for oropharyngeal SCC. 6,7 Within this population, pain, mucositis, dysphagia, dysgeusia, xerostomia, thick saliva, nausea, fatigue, and dermatitis are frequently reported during treatment, whereas xerostomia, dysphagia, fibrosis, and pain can become chronic issues known to negatively influence quality of life (QOL).…”