Prospective surveillance for otitis media with effusion among black infants in group child care

Zeisel, Susan A.; Roberts, Jason M.; Gunn, Elizabeth; Riggins, Rhodus; Evans, Gloria Ann; Roush, Jackson; Burchinal, Margaret; Henderson, Frederick W.

doi:10.1016/s0022-3476(95)70021-8

Cited by 25 publications

(7 citation statements)

References 17 publications

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“…These rates are dramatically higher than those in Tables V to VIII, which reflect OME present at cohort inception but of unknown prior duration. Conversely, another study 83 reported resolution rates by child for bilateral OME that began during the study and persisted for 4 months or longer. Resolution rates for one or both ears using liberal criterion were 16% by 1 month, 47% by 3 months, and 65% by 6 months.…”

Section: Resultsmentioning

confidence: 97%

Natural history of untreated otitis media

2003

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ObjectivelHypothesis:Data from cohort studies and untreated groups in randomized controlled trials can be identified through systematic literature review and synthesized with meta-analysis to estimate natural history of acute otitis media (AOM) and otitis media with effision (OME). Study D e s i p Systematic literature review and meta-analysis. Method Source articles were identified by MEDLINE search through August 2002 plus manual crosschecks of bibliographies and published meta-analyses. Data were abstracted independently by two investigators and combined with random effects meta-analysis to estimate spontaneous resolution, 95% confidence intervals (CI), and heterogeneity. Sensitivity analysis was performed. Results: Sixty-three articles met inclusion criteria AOM symptoms improved within 24 hours without antibiotics in 61% of children (95% CI, 50-72%), rising to 80% by 2 to 3 days (95% CI, 69-%).Suppurative complications were comparable if antibiotics were withheld (0.12%) or provided (0.24%). Children entered recurrent AOM trials with a mean rate of 5.5 or more annual episodes but averaged only 2.8 annual episodes while on placebo (95% CI, 2.2-3.4). No AOM episodes occurred in 41%, and only 17% remained otitis prone (3 or more episodes). OME after untreated AOM had 59% resolution by 1 month (95% CI, 50-68%) and 74% resolution by 3 months (95% CI, 68-SO%). OME of unknown duration had 28% spontaneous resolution by 3 months (95%, CI 14-41%), rising to 42% by 6 months (95% CI, 35-49%). In contrast, chronic OME had only 26% resolution by 6 months and 33% resolution by 1 year. Conclusions: The natural history of otitis media is very favorable. Combined estimates of spontaneous resolution provide a benchmark against which to judge new or established interventions. The need for surgery in children with recurrent AOM or chronic OME should be balanced against the likelihood of timely spontaneous resolution and the potential risk of learning, language, or other adverse se-

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Section: Resultsmentioning

confidence: 97%

Natural history of untreated otitis media

2003

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“…24,25,27,28 In brief, children's ears were examined weekly for the first 15 months of the study by 2 pediatric nurse practitioners trained in pneumatic otoscopy. Because of a protocol change, children's ears were examined biweekly after the 15th month of the study.…”

Section: Otitis Media Documentationmentioning

confidence: 99%

Early Childhood Otitis Media in Relation to Children's Attention-Related Behavior in the First Six Years of Life

et al. 2001

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“…19,20]. Despite some controversy [21], it appears that lan guage development and linguistically deter mined cognitive functions are affected in chil dren by severe and repeated middle-ear infec tions during the first years of their lives [22][23][24], Since detrimental effects of acoustic de privation on the maturation of the auditory pathway have been observed in various spe cies of experimental animals, it appears likely that a prolonged conductive hearing loss due to recurrent middle-ear infections in very young children may also affect auditory pro cessing.…”

Section: Introductionmentioning

confidence: 99%

Age-Dependent Effects of the Onset of a Conductive Hearing Loss on the Volume of the Cochlear Nucleus Subdivisions and the Expression of c- fos in the Mongolian Gerbil (Meriones unguiculatus)

Gleich

Strutz²

1997

Audiol Neurotol

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A monaural conductive hearing loss was induced by interrupting the chain of the middle ear ossicles on the right side in gerbils of four different age groups (Pl 2–14, P20–21, P42 and P84). The volumes of the cochlear nucleus subdivisions and the number of cells that expressed immunoreactivity for c-fos after noise stimulation were determined on the left and right side in the deprived animals, and in undeprived control animals when they reached the age of 6 months. The anteroventral cochlear nucleus on the deprived side was reduced in volume when the deprivation started before the age of 3 months. The other cochlear nucleus subdivisions showed no systematic age-dependent reductions. The expression of c-fos in the dorsal cochlear nucleus appeared more resistant to a hearing loss, with deprivation being more effective in younger animals. c-fos expression was also dramatically reduced in the ventral cochlear nucleus, regardless of age at the onset of hearing loss.

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Prospective surveillance for otitis media with effusion among black infants in group child care

Cited by 25 publications

References 17 publications

Natural history of untreated otitis media

Natural history of untreated otitis media

Early Childhood Otitis Media in Relation to Children's Attention-Related Behavior in the First Six Years of Life

Age-Dependent Effects of the Onset of a Conductive Hearing Loss on the Volume of the Cochlear Nucleus Subdivisions and the Expression of c- fos in the Mongolian Gerbil (Meriones unguiculatus)

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