Prospective surveillance for atypical pathogens in children with community-acquired pneumonia in Japan

Bamba, Masahiro; Jozaki, Keiji; Sugaya, Norio; Tamai, Shinya; Ishihara, Jun; Kori, Takeo; Shiro, Hiroyuki; Takeuchi, Yoshinao; Cho, Hideo; Nakao, Ayumi; Okano, Yuji; Kimura, Kazuhiro; Komiyama, Osamu; Nonoyama, Masato; Kobayashi, Ichiro; Kato, Tatsuo; Sunakawa, Keisuke

doi:10.1007/s10156-005-0422-y

Cited by 19 publications

(15 citation statements)

References 15 publications

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“…The higher prevalence of mycoplasma compared to chlamydia in children with CAP has been reported in a number of studies. 7 The available literature supports a low prevalence of C. pneumoniae infection in preschool aged children, i.e. ,5 years, but it is an important cause of pneumonia among children over five years old.…”

Section: Resultsmentioning

confidence: 96%

Atypical bacterial pathogens in community-acquired pneumonia in children: a hospital-based study

et al. 2009

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Section: Resultsmentioning

confidence: 96%

Atypical bacterial pathogens in community-acquired pneumonia in children: a hospital-based study

et al. 2009

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“…In a study based on the MIF C. pn IgM antibody [9], C. pn was the causative microorganism in 13.5% of the acute lower airway infection cases in children, showing that the primary infection [3,5,10,11]. In the ELISA method, consistency varies depending on the antigen used [12].…”

Section: Discussionmentioning

confidence: 99%

The validity of the criteria for primary infection of Chlamydophila pneumoniae in children by measuring ELISA IgM antibodies

Kamata

Obinata

Niizuma

et al. 2012

Journal of Infection and Chemotherapy

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“…MPP accounts for 10-40% of community-acquired pneumonia [1,6,9,12,20]. Usually, MPP is not associated with severe sequelae.…”

Section: Introductionmentioning

confidence: 99%

Ciliary ultrastructural abnormalities in Mycoplasma pneumoniae pneumonia in 22 pediatric patients

et al. 2011

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Mycoplasma pneumoniae pneumonia (MPP) is characterized by ciliary ultrastructural abnormalities that cause abnormal mucociliary function leading to refractory or persistent pneumonia. Herein, we analyzed ciliary ultrastructural defects in 22 children with MPP and determined the association of these defects with prognosis. Ciliary ultrastructural abnormalities occurred in all patients. Ciliated cells with loss of cilia occurred in 15. Cytoplasmic blebbing occurred in eight. Ambiguity of the "9 + 2" microtubule array occurred in six. Transposition or disarray of the peripheral microtubules occurred in five. Compound cilia occurred in three. Central complex defects occurred in three. Squamous metaplasia occurred in two. Compound cilia with multiple axonemes within a single outer sheath occurred in one. Multiple abnormalities occurred in 14. The recovery time in patients with multiple abnormalities was longer than that in patients with single abnormality. Patients with central complex defects required more than 1 month to recover. In conclusion, ciliated cells with loss of cilia, cytoplasmic blebbing, and ambiguity of the "9 + 2" microtubule array were the most commonly encountered abnormal findings in MPP. Multiple abnormalities, especially those associated with central complex defects, may indicate an unfavorable prognosis.

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Prospective surveillance for atypical pathogens in children with community-acquired pneumonia in Japan

Cited by 19 publications

References 15 publications

Atypical bacterial pathogens in community-acquired pneumonia in children: a hospital-based study

Atypical bacterial pathogens in community-acquired pneumonia in children: a hospital-based study

The validity of the criteria for primary infection of Chlamydophila pneumoniae in children by measuring ELISA IgM antibodies

Ciliary ultrastructural abnormalities in Mycoplasma pneumoniae pneumonia in 22 pediatric patients

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