Prospective study of the Perigee™ system for treatment of cystocele – our five‐year experience

Rane, Ajay; Iyer, Jay; Kannan, K.; Corstiaans, Audrey

doi:10.1111/j.1479-828x.2011.01384.x

Cited by 22 publications

(14 citation statements)

References 27 publications

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“…Erosion rates with other apical and anterior correction systems are similar: Letouzey et al found a rate of 2.7 % using the Uphold system, and De Landsheere et al found a rate of 2.5 % using the Prolift system [26,29]. In a prospective study of the Perigee system in 376 patients, the erosion rate was higher, at 11.1 % [24]. Vaginal pain was defined as pain provoked on vaginal examination.…”

Section: Discussionmentioning

confidence: 91%

“…Moore et al, in 114 patients with anterior wall prolapse of stage ≥2 managed using the Perigee system, found an objective success rate of 88.5 %, but without apical assessment [23]. In a prospective study in 376 patients with cystocele of stage ≥3 managed with the Perigee system, Rane et al found a success rate of 94.3 % in the anterior compartment at 5 years [24]. Only Lo et al, in patients with pelvic organ prolapse, 57 managed with the Elevate Ant system and 61 with the Perigee system, found significantly better point-C correction at 1 year with the Elevate Ant system (8.07 preoperatively versus −10.50 at 1 year) compared with the Perigee system associated with sacrospinous fixation (p < 0.001) [25].…”

Section: Discussionmentioning

confidence: 99%

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A retrospective comparison of two vaginal mesh kits in the management of anterior and apical vaginal prolapse: long-term results for apical fixation and quality of life

et al. 2016

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The use of the Elevate Ant mesh was associated with significantly better apical correction at 2 years. Function improved in both groups, but with a significantly better PFDI-20 score in the Elevate Ant group at 1 and 2 years. The postoperative stress urinary incontinence rate, however, tended to be greater in the Elevate Ant group. The results need confirming with longer follow-up of these cohorts and in randomized studies.

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Section: Discussionmentioning

confidence: 91%

Section: Discussionmentioning

confidence: 99%

A retrospective comparison of two vaginal mesh kits in the management of anterior and apical vaginal prolapse: long-term results for apical fixation and quality of life

et al. 2016

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“…Safety and efficacy of the Perigee TM system have been documented with recent five-year data. 8 However, failure (that is, pullthrough) of those anchoring arms is not uncommon. 9 Due to increasing emphasis on the importance of apical support for the anterior compartment, 10 mesh kit systems such as the Anterior Elevate TM (American Medical Systems) were introduced.…”

Section: Introductionmentioning

confidence: 99%

A comparison of two different mesh kit systems for anterior compartment prolapse repair

Wong

Shek

Rane

et al. 2014

Aust NZ J Obst Gynaeco

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Background and Aim: Mesh reinforcement is considered an effective method for anterior compartment prolapse repair. Two common methods of mesh reinforcement involve either transobturator fixation (eg Perigee TM ) or lateral and apical anchoring (eg Anterior Elevate TM ). The aim of this study was to assess subjective and objective outcomes after Anterior Elevate and Perigee mesh kit surgery. Materials and Methods: This was a surgical audit of patients after anterior colporrhaphy (AC) with mesh reinforcement, undertaken at three tertiary urogynaecological centres. All patients were assessed for prolapse recurrence, which was defined as either (i) symptoms of prolapse (vaginal lump/dragging), (ii) ICS POPQ ≥ Stage 2, or (iii) bladder descent ≥10 mm below the symphysis pubis on transperineal ultrasound. Mesh co-ordinates and organ descent on Valsalva were determined relative to the inferior symphyseal margin. Results: Two hundred and twenty-nine patients with anterior compartment mesh (138 Perigee, 91 Elevate) were assessed at a median follow-up of 1.09 years (IQR 0.65-2.01). On assessment, 24% (n = 55) had symptoms of prolapse recurrence, 46% (n = 106) had a clinical recurrence, and 41% (n = 95) a recurrent cystocele sonographically. All objective results favoured the Perigee group. The superiority of the Perigee kit remained highly significant (P < 0.0001 for all clinical and ultrasound measures of prolapse recurrence) on multivariate analysis. Conclusions: This retrospective analysis suggests that apical anchoring such as Anterior Elevate mesh system does not necessarily confer an advantage over the original transobturator mesh fixation technique for anterior compartment reconstruction.

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“…[1,2] Cystocele [anterior vaginal wall prolapse (AVWP)] is the most common type of POP in women and is due to herniation of the bladder through anterior vaginal wall. [3] It may be lateral or central due to loss of support or weakness of the pubocervical facia between bladder and vagina. [4] Female stress urinary incontinence (SUI) is a significant health problem which is considered to be a common condition for adult female with prevalence rates ranging from 12.8 to 46%.…”

Section: Introductionmentioning

confidence: 99%

Transobturator four arms mesh in the surgical management of stress urinary incontinence with cystocele

Sherif

Othman

Eldkhakhany

et al. 2017

Turkish Journal of Urology

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Objective: This study aims to evaluate safety and efficacy of four arms polypropylene mesh in the longterm follow-up in the management of stress urinary incontinence (SUI) associated with cystocele. Material and methods:This prospective study was conducted on 50 female patients with SUI associated with cystocele. Patients underwent placement of transobturator four-arms mesh implants. Stress incontinence was evaluated using cough stress test with and without prolapse reduction, Stamey's grading of SUI, the validated Arabic version of the International Consultation on Incontinence Questionnaire-Short Form and King Health Questionnaire forms. Perioperative parameters evaluated included age, body mass index, grade of SUI, time of procedure, hospital stay after surgery, difference between pre-, and postoperative serum hemoglobin values, and need for blood transfusion. Follow-up visits were planned at 3, 9 and 18 months after surgery. Results:The mean operative time was 37.4±10.2 (25-60) minutes. Blood transfusion was not required. The mean hospital stay was 30.5±10 (24-48) hrs. Five (10%) patients had fever and urinary tract infections were noticed in five (10%) patients. Two (4%) women had urine retention after catheter removal and vaginal mesh erosion was present in one (2%) patient. Forty (80%) patients were cured from SUI, 8 (16%) patients were improved and 2 (4%) patients failed to respond. Conclusion:Cystocele associated with SUI can be repaired with transobturator four-arms mesh with promising results, improved quality of life, and tolerable side effects.

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Prospective study of the Perigee™ system for treatment of cystocele – our five‐year experience

Cited by 22 publications

References 27 publications

A retrospective comparison of two vaginal mesh kits in the management of anterior and apical vaginal prolapse: long-term results for apical fixation and quality of life

A retrospective comparison of two vaginal mesh kits in the management of anterior and apical vaginal prolapse: long-term results for apical fixation and quality of life

A comparison of two different mesh kit systems for anterior compartment prolapse repair

Transobturator four arms mesh in the surgical management of stress urinary incontinence with cystocele

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