Prospective Study of Intracranial Translucency and the Posterior Brain in Normal Fetuses at the 11‐ to 13‐Week Scan

Abstract

Intracranial translucency can be prospectively identified by trained sonographers in 96% of normal fetuses at 11 to 13 weeks. Measurements of brain stem and brain stem-occipital bone diameters are reproducible.

Intracranial translucency assessment at first trimester nuchal translucency ultrasound

“…Supine fetal position is consistently reported as significantly associated with IT visualization, as we also found in our study. However, authors have differed when assessing the affect of maternal BMI.…”

“…Mean maternal age was 29.2 years (16-42), mean maternal BMI was 24.5 kg/m 2 (14.7-58.4), mean CRL was 65.6 mm (47-84) and mean nuchal translucency thickness was 1.8 mm (0.9-7.7). Placental location was as follows: anterior (366), posterior (337), bilobed (1), lateral (10) and fundal (28). Fetal lie was as follows: supine (679), prone (8) and variable (55).…”

Failure of getting intracranial translucency image in posterior fossa in the examination of singleton pregnancies at 11–13 weeks of gestation: reasons and outcomes

“…This rate was between 0% and 5% in other series. [4,[19][20][21] When we reviewed the literature, we found out that many studies on IT issue were rather archive studies which investigated recorded images retrospectively. [13,22,23] When these examinations were reevaluated, it was found that any fluid image seen in posterior fossa of some fetuses could be measured as IT by accident.…”

Normal Intracranial Translucency Values During the First Trimester of Gestation in a Latin American Population

“…By performing sonographic examinations in this period (apart from other advantages), it is possible to identify signs of fetal malformations and various markers of aneuploidy. 2,[9][10][11][12][13] It has been shown that an alteration in the intracranial translucency values between 11 weeks and 13 weeks 6 days suggests a central nervous system defect. [14][15][16][17][18][19][20][21] Reduced intracranial translucency values have been associated with open spina bifida, 3,7,22,23 which is considered a congenital defect associated with high perinatal mortality and high long-term morbidity.…”