Prospective Study of Indwelling Central Venous Catheter-Related Complications in Children With Broviac or Clampless Valved Catheters

Abstract

There were no major differences in the incidence of mechanical or infectious complications between the two devices. Malfunction was more frequent in Broviac catheters, whereas catheter displacement occurred more frequently in clampless valved catheters. These results show the importance of central venous catheter-related mechanical complications in the management of children with hematologic or oncologic malignancies.

A prospective 7-year survey on central venous catheter-related complications at a single pediatric hospital

“…Despite the unbalanced distribution of CVC type, our findings are consistent with previous reports. The increase in infectious 13 (5) 19 (2) 0 (0) 11 (4) 8 (1) 7 (3) 12 (2) OR (95%CI) (7) 105 (29) 85 (13) 58 (21) 133 (16) 10 (13) 46 (16) 87 (16) 42 (17) 101 (15) OR (95%CI) (3) 17 (5) 24 (4) 7 (3) 26 (3) 5 (7) 11 (4) 15 (3) 14 (6) 17 (3) OR (95%CI) risk when using externalized CVCs is probably offset by their atraumatic access, thereby justifying the continued use of this CVC type in all Italian pediatric cancer centers. In our study, the underlying disease was not a significant determinant of risk, in contrast with other studies which reported a higher risk of infection in children with acute leukemia [5,28].…”

The safety of central line placement prior to treatment of pediatric acute lymphoblastic leukemia

“…Previous investigations have reported major complications associated with central lines, including thrombotic occlusion, infection, and mechanical malfunction 5–8. It has been suggested that the most common complication is infection, with thrombosis being a major complication as well 6,7.…”

Use of an ethanol lock to prevent catheter-related infections in children with short bowel syndrome

“…A common morbidity associated with indwelling CVCs is catheter-related infection (CRI) with the incidence of infection ranging from 3% to 60% over the life span of the catheter [1,2]. Current Infectious Disease Society of America (IDSA) guidelines state that infected tunneled CVCs may be salvaged if the infection is uncomplicated and caused by coagulase-negative Staphylococcus spp, S aureus, or Gramnegative bacilli [1].…”