Prospective randomized evaluation of diode‐laser and cryotherapy in prethreshold retinopathy of prematurity

Azad, Raj Vardhan; L, Pasumala; Kumar, Harsh; Talwar, Dinesh; Pal, Raj Kumar; Paul, Vinod K.; Chandra, Parijat

doi:10.1111/j.1442-9071.2004.00812.x

Cited by 12 publications

(7 citation statements)

References 16 publications

(14 reference statements)

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“…It causes less effusion than cryotherapy and has at least as good results from an anatomical and visual standpoint (10)(11)(12) . In the not so distant future, it may be that pharmacologic therapy will be possible (7,(13)(14)(15)(16) .…”

Section: Discussionmentioning

confidence: 99%

“…Besides the immediate short-term results it seems that laser therapy may also be beneficial in respect to longterm functional and visual outcome. Eyes treated with cryotherapy have been found to be significantly more myopic than those treated with laser photocoagulation (10)(11)(12)17) . Although laser has definite advantages, cryotherapy can be considered as an alternative modality of treatment in developing countries due to economic reasons (10)(11)(12) .…”

Section: Discussionmentioning

confidence: 99%

“…Eyes treated with cryotherapy have been found to be significantly more myopic than those treated with laser photocoagulation (10)(11)(12)17) . Although laser has definite advantages, cryotherapy can be considered as an alternative modality of treatment in developing countries due to economic reasons (10)(11)(12) . Laser complications of the anterior segment can include burns to the cornea, iris and tunica vasculosa lentis with induction of cataract, anterior ischemia, bleeding into the anterior and posterior chambers (12,(18)(19) .…”

Section: Discussionmentioning

confidence: 99%

“…Although laser has definite advantages, cryotherapy can be considered as an alternative modality of treatment in developing countries due to economic reasons (10)(11)(12) . Laser complications of the anterior segment can include burns to the cornea, iris and tunica vasculosa lentis with induction of cataract, anterior ischemia, bleeding into the anterior and posterior chambers (12,(18)(19) . In our study none of these complications occurred after laser application.…”

Section: Discussionmentioning

confidence: 99%

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Efficacy and safety of green laser photocoagulation for threshold retinopathy of prematurity

Lira¹,

Calheiros²,

Oliveira³

et al. 2008

Arq. Bras. Oftalmol.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Efficacy and safety of green laser photocoagulation for threshold retinopathy of prematurity

Lira¹,

Calheiros²,

Oliveira³

et al. 2008

Arq. Bras. Oftalmol.

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“…Laser has many advantages over cryotherapy. [1011] There is less post-treatment pain, adnexal edema, exudative retinal detachment, vitreoretinal traction, and vitreous hemorrhage, due to reduced breakdown of the blood-retinal barrier. Use of topical anesthesia reduces systemic complications such as bradycardia or apnea.…”

Section: Instrumentation Materials and Preparation For Laser Therapymentioning

confidence: 99%

Technical aspects of laser treatment for acute retinopathy of prematurity under topical anesthesia

Jalali

Azad

Trehan

et al. 2010

Indian J Ophthalmol

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Retinopathy of prematurity (ROP) is a significant cause of childhood blindness. The criteria for laser therapy have been revised from threshold ROP to include the earlier stage of high-risk prethreshold ROP. Laser photocoagulation is an established technique for the treatment of ROP. However, the detailed procedure and techniques for laser photocoagulation have not yet been published. Adequate and appropriate laser photocoagulation for ROP is different from the application of lasers in adult retinal vascular diseases, and many ophthalmologists need to be trained in this technique if the outreach of ROP treatment programs is to improve. Laser under topical anesthesia has been practiced in India as a preferred modality especially due to logistics and risks of general anesthesia in these pre-term babies. We discuss the details of the technique as practiced at tertiary care ophthalmic hospitals in India, so that the nuances in treatment parameters and clinical decision-making can be usefully applied to ophthalmic practice. This will ultimately lead to safe and effective treatment delivery in ROP.

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The Male to Female Ratio in Treatment-Warranted Retinopathy of Prematurity

et al. 2022

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ImportanceLiterature and anecdotal evidence suggest a relationship between male sex and retinopathy of prematurity (ROP). It is not known whether a difference, if present, is sex-related pathophysiologic predisposition or sex difference in meeting ROP screening criteria.ObjectiveTo evaluate the association of sex with the development of treatment-warranted ROP.Data SourcesPubMed, Embase, and Web of Science databases were searched from 2000 to 2022. The search strategy used keywords including retinopathy of prematurity or ROP or retrolental fibroplasia and treatment or anti-VEGF or bevacizumab or ranibizumab or aflibercept or conbercept or laser or cryotherapy and gender or sex or male or female and medical subject headings terms.Study SelectionAll studies reporting on treatment with anti–vascular endothelial growth factor, laser photocoagulation, and/or cryotherapy for ROP were identified. Studies reporting sex distribution in the treatment group were included in the meta-analysis. Exclusion criteria included case reports, case series of fewer than 10 treated patients, systematic reviews, conference abstracts, letters to the editor, animal studies, and non-English records.Data Extraction and SynthesisTwo reviewers independently screened and extracted the data following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The proportions of treated male and female infants were combined using random-effects meta-analysis.Main Outcomes and MeasuresNumbers and percentages of male and female infants treated for ROP.ResultsOf 11 368 identified studies, 316 met inclusion criteria, yielding a total of 31 026 treated patients. A higher percentage of male infants were treated for ROP (55% [95% CI, 0.54%-0.55%]), with low heterogeneity between studies (I2 = 34%; P &lt; .001). Thirty-eight studies reported sex distribution in the screened population (170 053 patients; 92 612 [53%] male vs 77 441 [47%] female). There was no significant difference in the odds of receiving treatment between screened male and female infants (pooled odds ratio, 1.04 [95% CI, 0.91-1.18]; P = .67).Conclusions and RelevanceMore male infants are treated for ROP than female infants. This could be due to a known relative pathophysiological fragility of preterm male infants in addition to a difference in ROP screening rates, with more male infants meeting the criteria than female infants. These findings have implications for future studies and may prompt more careful clinical monitoring of male neonates.

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Prospective randomized evaluation of diode‐laser and cryotherapy in prethreshold retinopathy of prematurity

Cited by 12 publications

References 16 publications

Efficacy and safety of green laser photocoagulation for threshold retinopathy of prematurity

Efficacy and safety of green laser photocoagulation for threshold retinopathy of prematurity

Technical aspects of laser treatment for acute retinopathy of prematurity under topical anesthesia

The Male to Female Ratio in Treatment-Warranted Retinopathy of Prematurity

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