Prospective randomized comparison of applying media with or without antioxidants during the entire IVF procedure on sibling gametes, subsequent embryo culture and single-vitrified blastocyst transfer
Shigetoshi Mizumoto,
Yozo Nagao,
Hitomi Watanabe
et al.
Abstract:Background
To investigate the effect of antioxidants (AOX) on human embryo development and clinical outcome when used during all IVF procedures.
Methods
Prospective randomized single-centre study, where cumulus-oocyte complexes and semen samples from 127 treatment cycles were equally split between study and control (with/without AOX). The primary endpoint was Day 5/6 good quality blastocyst (GQB) rate / Metaphase-II (M-II) oocyte.
Results
The GQB rate between the study group and control was almost significa… Show more
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