Prospective predictors of suicide and suicide attempts in 1,556 patients with bipolar disorders followed for up to 2 years

Marangell, Lauren B.; Bauer, Mark S.; Dennehy, Ellen B.; Wisniewski, Stephen R.; Allen, Michael; Miklowitz, David J.; Oquendo, María A.; Frank, Ellen; Perlis, Roy H.; Martinez, J. Michael; Fagiolini, Andrea; Otto, Michael W.; Chessick, Cheryl A.; Zboyan, Holly A.; Miyahara, Sachiko; Sachs, Gary S.; Thase, Michael E.

doi:10.1111/j.1399-5618.2006.00369.x

Cited by 124 publications

(111 citation statements)

References 42 publications

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“…Factors reported to be significantly associated with suicidal attempt include female sex, younger age of illness onset, depressive polarity of first illness episode, depressive polarity of current or more recent episode, comorbid anxiety disorder, comorbid SUD, comorbid cluster B/borderline personality disorder, first‐degree family history of suicide, and previous suicide attempts. Only male sex and first‐degree family history of suicide have been significantly associated with suicide deaths 50, 51. The periods during and following hospital admission further represent times of particularly high risk, with 14% of suicides occurring during an inpatient stay and another 26% within 6 weeks of discharge 47, 52…”

Section: Foundations Of Managementmentioning

confidence: 99%

Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients with bipolar disorder

et al. 2018

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The Canadian Network for Mood and Anxiety Treatments (CANMAT) previously published treatment guidelines for bipolar disorder in 2005, along with international commentaries and subsequent updates in 2007, 2009, and 2013. The last two updates were published in collaboration with the International Society for Bipolar Disorders (ISBD). These 2018 CANMAT and ISBD Bipolar Treatment Guidelines represent the significant advances in the field since the last full edition was published in 2005, including updates to diagnosis and management as well as new research into pharmacological and psychological treatments. These advances have been translated into clear and easy to use recommendations for first, second, and third‐ line treatments, with consideration given to levels of evidence for efficacy, clinical support based on experience, and consensus ratings of safety, tolerability, and treatment‐emergent switch risk. New to these guidelines, hierarchical rankings were created for first and second‐ line treatments recommended for acute mania, acute depression, and maintenance treatment in bipolar I disorder. Created by considering the impact of each treatment across all phases of illness, this hierarchy will further assist clinicians in making evidence‐based treatment decisions. Lithium, quetiapine, divalproex, asenapine, aripiprazole, paliperidone, risperidone, and cariprazine alone or in combination are recommended as first‐line treatments for acute mania. First‐line options for bipolar I depression include quetiapine, lurasidone plus lithium or divalproex, lithium, lamotrigine, lurasidone, or adjunctive lamotrigine. While medications that have been shown to be effective for the acute phase should generally be continued for the maintenance phase in bipolar I disorder, there are some exceptions (such as with antidepressants); and available data suggest that lithium, quetiapine, divalproex, lamotrigine, asenapine, and aripiprazole monotherapy or combination treatments should be considered first‐line for those initiating or switching treatment during the maintenance phase. In addition to addressing issues in bipolar I disorder, these guidelines also provide an overview of, and recommendations for, clinical management of bipolar II disorder, as well as advice on specific populations, such as women at various stages of the reproductive cycle, children and adolescents, and older adults. There are also discussions on the impact of specific psychiatric and medical comorbidities such as substance use, anxiety, and metabolic disorders. Finally, an overview of issues related to safety and monitoring is provided. The CANMAT and ISBD groups hope that these guidelines become a valuable tool for practitioners across the globe.

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Section: Foundations Of Managementmentioning

confidence: 99%

Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients with bipolar disorder

et al. 2018

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“…34 Marangell et al, in a sample of 1,556 individuals with bipolar I and bipolar II, also showed that previous attempters reported more suicidal ideation at baseline and an increased risk for suicide attempts during follow-up. 35 Studies have also suggested that suicidal ideation is mostly associated with depressive and mixed episodes, 20,22 indicating that suicidal ideation can vary across different mood states. In a second analysis of the same sample during different episodes, Valtonen et al found marked differences regarding the level of.…”

Section: Stress-diathesis Modelmentioning

confidence: 99%

Suicidal ideation and suicide attempts in bipolar disorder type I: an update for the clinician

Abreu

Lafer

Baca‐García

et al. 2009

Rev. Bras. Psiquiatr.

100

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“…Both above mentioned disorders, have been associated with increased risk for suicide (Rihmer 2007). Patients with BD have a suicide rate 30 times higher than the general population and 25-50% of these patients will attempt suicide once in their lifetime (Marangell et al 2006). Fifteen percent of those who attempted suicide eventually make complete suicide (Izci et al 2016).…”

Section: Introductionmentioning

confidence: 99%

The Temperament and Character Traits in Patients With Major Depressive Disorder and Bipolar Affective Disorder With and Without Suicide Attempt

Erić

Ćurković

et al. 2017

Psychiat Danub

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Prospective predictors of suicide and suicide attempts in 1,556 patients with bipolar disorders followed for up to 2 years

Abstract: These results indicate that patients with bipolar disorder who present with a history of SAs are over four times as likely to have a subsequent SA or completion. Further studies are needed to evaluate and prevent future attempts in this high-risk cohort.

Cited by 124 publications

References 42 publications

Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients with bipolar disorder

Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients with bipolar disorder

Suicidal ideation and suicide attempts in bipolar disorder type I: an update for the clinician

The Temperament and Character Traits in Patients With Major Depressive Disorder and Bipolar Affective Disorder With and Without Suicide Attempt

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