Prospective MRI score to predict negative EULAR response in patients with rheumatoid arthritis (RA) before therapy-escalation to a biological therapy

Sewerin, Philipp; Vordenbaeumen, S.; Brinks, Ralph; Ostendorf, Benedikt

doi:10.1136/annrheumdis-2017-211257

Ann Rheum Dis

2017

DOI: 10.1136/annrheumdis-2017-211257

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Prospective MRI score to predict negative EULAR response in patients with rheumatoid arthritis (RA) before therapy-escalation to a biological therapy

Philipp Sewerin

S. Vordenbaeumen

Ralph Brinks

et al.

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“…We thank Sewerin et al 1 for the data they have provided on the predictive role of MRI for clinical response in rheumatoid arthritis (RA). This study follows on from our previous study demonstrating the predictive value of MRI for radiographic damage progression 2.…”

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Is MRI a predictive biomarker for clinical response to biologics in rheumatoid arthritis?

2017

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Is MRI a predictive biomarker for clinical response to biologics in rheumatoid arthritis?

2017

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Biomarker und Bildgebung zur Diagnose und Stratifizierung der rheumatoiden Arthritis und Spondylarthritis im BMBF-Verbund ArthroMark

et al. 2018

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Rheumatic diseases are among the most common chronic inflammatory disorders. Besides severe pain and progressive destruction of the joints, rheumatoid arthritis (RA), spondyloarthritides (SpA) and psoriatic arthritis (PsA) impair working ability, reduce quality of life and if treated insufficiently may enhance mortality. With the introduction of biologics to treat these diseases, the demand for biomarkers of early diagnosis and therapeutic stratification has been growing continuously. The main goal of the consortium ArthroMark is to identify new biomarkers and to apply modern imaging technologies for diagnosis, follow-up assessment and stratification of patients with RA, SpA and PsA. With the development of new biomarkers for these diseases, the ArthroMark project contributes to research in chronic diseases of the musculoskeletal system. The cooperation between different national centers will utilize site-specific resources, such as biobanks and clinical studies for sharing and gainful networking of individual core areas in biomarker analysis. Joint data management and harmonization of data assessment as well as best practice characterization of patients with new imaging technologies will optimize quality of marker validation.

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Prospective MRI score to predict negative EULAR response in patients with rheumatoid arthritis (RA) before therapy-escalation to a biological therapy

Cited by 2 publications

References 2 publications

Is MRI a predictive biomarker for clinical response to biologics in rheumatoid arthritis?

Is MRI a predictive biomarker for clinical response to biologics in rheumatoid arthritis?

Biomarker und Bildgebung zur Diagnose und Stratifizierung der rheumatoiden Arthritis und Spondylarthritis im BMBF-Verbund ArthroMark

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