Prospective Evaluation of the Risk of Serious Bacterial Infection in Children Who Present to the Emergency Department With Hyperpyrexia (Temperature of 106°F or Higher)

Trautner, Barbara W.; Caviness, A. Chantal; Gerlacher, Gary R.; Demmler, Gail J.; Macias, Charles G.

doi:10.1542/peds.2005-2823

Cited by 73 publications

(66 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…23 Hyperthermia should be addressed promptly, because at temperatures above 41°C to 42°C, adverse physiologic effects begin to occur. 7,9,24 Studies of health care workers, including physicians, have revealed that most believe that the risk of heat-related adverse outcomes is increased with temperatures above 40°C (104°F), although this belief is not justified. 5,23,[25][26][27] A child with a temperature of 40°C (104°F) attributable to a simple febrile illness is quite different from a child with a temperature of 40°C (104°F) attributable to heat stroke.…”

Section: Physiology Of Fevermentioning

confidence: 99%

Fever and Antipyretic Use in Children

Sullivan¹,

Farrar²

2011

Pediatrics

363

313

View full text Add to dashboard Cite

Fever in a child is one of the most common clinical symptoms managed by pediatricians and other health care providers and a frequent cause of parental concern. Many parents administer antipyretics even when there is minimal or no fever, because they are concerned that the child must maintain a “normal” temperature. Fever, however, is not the primary illness but is a physiologic mechanism that has beneficial effects in fighting infection. There is no evidence that fever itself worsens the course of an illness or that it causes long-term neurologic complications. Thus, the primary goal of treating the febrile child should be to improve the child's overall comfort rather than focus on the normalization of body temperature. When counseling the parents or caregivers of a febrile child, the general well-being of the child, the importance of monitoring activity, observing for signs of serious illness, encouraging appropriate fluid intake, and the safe storage of antipyretics should be emphasized. Current evidence suggests that there is no substantial difference in the safety and effectiveness of acetaminophen and ibuprofen in the care of a generally healthy child with fever. There is evidence that combining these 2 products is more effective than the use of a single agent alone; however, there are concerns that combined treatment may be more complicated and contribute to the unsafe use of these drugs. Pediatricians should also promote patient safety by advocating for simplified formulations, dosing instructions, and dosing devices.

show abstract

Section: Physiology Of Fevermentioning

confidence: 99%

Fever and Antipyretic Use in Children

Sullivan¹,

Farrar²

2011

Pediatrics

363

313

View full text Add to dashboard Cite

show abstract

“…The height of body temperature may have some diagnostic and prognostic implications. Some studies have attributed high grade fevers in infants to serious bacterial infections [33], although others have also shown that children with high fevers are at equally high risk for serious bacterial infections and for viral illness [34].…”

Section: Classification Types and Patterns Of Fevermentioning

confidence: 99%

Fever, fever patterns and diseases called ‘fever’ – A review

Ogoina

2011

Journal of Infection and Public Health

233

163

View full text Add to dashboard Cite

Summary Fever is a prominent feature of disease since antiquity. The febrile response is orchestrated by the central nervous system through endocrine, neurological, immunological and behavioural mechanisms. Other than a regulated rise in body temperature, fever is often accompanied by various sickness behaviours, changes in metabolic and physiological characteristics of body systems and alterations in immune responses. Fever and the febrile response, therefore, remain significant contributors to the pathogenesis, clinical presentation and outcome of many illnesses and diseases.This review highlights the pathophysiology of the febrile response and describes the fever types and patterns, including their clinical significance. The various medical illnesses called ''fever'' are also listed and the origins of their appellations discussed.

show abstract

“…11,29,36,[45][46][47][48][49][50][51][52][53][54][55][56][57][58][59][60][61] All but two 18,20 of these included children based on the presence of fever and six cases 45,50,[52][53][54]60 were based on the absence of localising signs or focus of infection. A further six studies reported outcomes on bacteraemia, [62][63][64][65][66][67] and five of them [62][63][64]66,67 included children with fever.…”

Section: Outcomes Reportedmentioning

confidence: 99%

Systematic review and validation of prediction rules for identifying children with serious infections in emergency departments and urgent-access primary care.

Thompson

Bruel²,

Verbakel³

et al. 2012

Health Technol Assess

239

View full text Add to dashboard Cite

How to obtain copies of this and other HTA programme reports An electronic version of this title, in Adobe Acrobat format, is available for downloading free of charge for personal use from the HTA website (www.hta.ac.uk). A fully searchable DVD is also available (see below).Printed copies of HTA journal series issues cost £20 each (post and packing free in the UK) to both public and private sector purchasers from our despatch agents.Non-UK purchasers will have to pay a small fee for post and packing. For European countries the cost is £2 per issue and for the rest of the world £3 per issue. How to order:-fax (with credit card details) -post (with credit card details or cheque) -phone during office hours (credit card only).Additionally the HTA website allows you to either print out your order or download a blank order form. Contact details are as follows:Synergie UK (HTA Department) Digital House, The Loddon Centre Wade Road Basingstoke Hants RG24 8QW Email: orders@hta.ac.uk Tel: 0845 812 4000 -ask for 'HTA Payment Services' (out-of-hours answer-phone service) Fax: 0845 812 4001 -put 'HTA Order' on the fax header Payment methods Paying by chequeIf you pay by cheque, the cheque must be in pounds sterling, made payable to University of Southampton and drawn on a bank with a UK address.Paying by credit card You can order using your credit card by phone, fax or post. SubscriptionsNHS libraries can subscribe free of charge. Public libraries can subscribe at a reduced cost of £100 for each volume (normally comprising 40-50 titles). The commercial subscription rate is £400 per volume (addresses within the UK) and £600 per volume (addresses outside the UK). Please see our website for details. Subscriptions can be purchased only for the current or forthcoming volume.How do I get a copy of HTA on DVD?Please use the form on the HTA website (www.hta.ac.uk/htacd/index.shtml). HTA on DVD is currently free of charge worldwide.The website also provides information about the HTA programme and lists the membership of the various committees. HTA NIHR Health Technology Assessment programmeThe Health Technology Assessment (HTA) programme, part of the National Institute for Health Research (NIHR), was set up in 1993. It produces high-quality research information on the effectiveness, costs and broader impact of health technologies for those who use, manage and provide care in the NHS. 'Health technologies' are broadly defined as all interventions used to promote health, prevent and treat disease, and improve rehabilitation and long-term care. The research findings from the HTA programme directly influence decision-making bodies such as the National Institute for Health and Clinical Excellence (NICE) and the National Screening Committee (NSC). HTA findings also help to improve the quality of clinical practice in the NHS indirectly in that they form a key component of the 'National Knowledge Service' . The HTA programme is needs led in that it fills gaps in the evidence needed by the NHS. There are three routes to the start of projec...

show abstract

Prospective Evaluation of the Risk of Serious Bacterial Infection in Children Who Present to the Emergency Department With Hyperpyrexia (Temperature of 106°F or Higher)

Abstract: BACKGROUND-Previous studies of children with temperatures ≥106°F (hyperpyrexia) disagree as to whether hyperpyrexia confers a high risk of serious bacterial infection.

Cited by 73 publications

References 14 publications

Fever and Antipyretic Use in Children

Fever and Antipyretic Use in Children

Fever, fever patterns and diseases called ‘fever’ – A review

Systematic review and validation of prediction rules for identifying children with serious infections in emergency departments and urgent-access primary care.

Contact Info

Product

Resources

About