Prospective Evaluation of Pain Relief in 100 Patients Undergoing Percutaneous Vertebroplasty: Results and Follow-up

McGraw, J. Kevin; Lippert, John; Minkus, Kirk D.; Rami, P.; Davis, Thomas M.; Budzik, Ronald F

doi:10.1016/s1051-0443(07)61770-9

Cited by 242 publications

(163 citation statements)

References 13 publications

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“…Patients treated with the procedure reported complete or partial pain relief immediately after the procedure: 24 h after in 88% of cases of osteoporotic fractures and in 84% of cases of neoplastic fractures. These data confirm the high success rates reported by other authors [4,5,[18][19][20][21]. No patient reported pain worsening, whereas patients who failed to benefit significantly from the procedure were affected by fractures more than 6 months old.…”

Section: Fig 3ab Fuga DI Cemento In Una Vena Perivertebrale Immagisupporting

confidence: 90%

“…I pazienti che abbiamo sottoposto alla procedura hanno riferito la scomparsa o la significativa riduzione del dolore immediatamente dopo la procedura e dopo 24 ore nel 88% dei casi quando colpiti da crollo osteoporotico, e nel 84% quando affetti da localizzazione neoplastica. Questi dati confermano quelli di altri autori riportanti alte percentuali di successo [4,5,[18][19][20][21]. In nessun soggetto si è avuto un peggioramento della sintomatologia, mentre i pazienti che non hanno tratto sollievo in maniera significativa dal trattamento erano affetti da fratture datate oltre sei mesi.…”

Section: Fig 3ab Fuga DI Cemento In Una Vena Perivertebrale Immagiunclassified

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Percutaneous vertebroplasty: the follow-up

et al. 2008

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Purpose. This article reports on our experience treating vertebral fractures with percutaneous vertebroplasty. A clinical and imaging follow-up designed to identify the early (especially pulmonary embolism of bone cement) and late complications of the technique is proposed. Material and methods. On the basis of the current guidelines, 101 patients were selected: 64 osteoporotic and 37 neoplastic. A total of 173 vertebrae were treated. Procedures were performed with both computed tomography and fluoroscopic guidance. Residual pain was evaluated with a visual analogue scale score immediately after vertebroplasty and 1, 15, 30, 90, 180 and 270 days later. Spine and chest radiographs were obtained 24 h after vertebroplasty; spine radiography was repeated 30 days later. Results. Therapeutic success was obtained in 88% of osteoporotic patients and in 84% of neoplastic patients. Pulmonary cement emboli were identified in four patients, all of whom were asymptomatic. Conclusions. Percutaneous vertebroplasty is a safe and

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Section: Fig 3ab Fuga DI Cemento In Una Vena Perivertebrale Immagisupporting

confidence: 90%

Section: Fig 3ab Fuga DI Cemento In Una Vena Perivertebrale Immagiunclassified

Percutaneous vertebroplasty: the follow-up

et al. 2008

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“…However, these operations have significant morbidity related to the surgical approach, potential blood loss, and extensive dissection. More recently, minimally invasive surgical interventions have been utilized in treating vertebral metastases [18,20,30].…”

Section: Introductionmentioning

confidence: 99%

The effect of pre-vertebroplasty tumor ablation using laser-induced thermotherapy on biomechanical stability and cement fill in the metastatic spine

et al. 2007

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A biomechanical study comparing simulated lytic vertebral metastases treated with laser-induced thermotherapy (LITT) and vertebroplasty versus vertebroplasty alone. To investigate the effect of tumor ablation using LITT prior to vertebroplasty on biomechanical stability and cement fill patterns in a standardized model of spinal metastatic disease. Vertebroplasty in the metastatic spine is aimed at reducing pain, but is associated with risk of cement extravasation in up to 10%. Six pairs of fresh-frozen cadaveric thoracolumbar spinal motion segments were tested in axial compression intact, with simulated metastases and following percutaneous vertebroplasty with or without LITT. Canal narrowing under load, pattern of cement fill, load to failure, and LITT temperature and pressure generation were collected. In all LITT specimens, cement filled the defect without extravasation. The canal extravasation rate was 33% in specimens treated without LITT. LITT and vertebroplasty yielded a trend toward improved posterior wall stability (P = 0.095) as compared to vertebroplasty alone. Moderate rises in temperature and minimal pressure generation was seen during LITT. In this model, elimination of tumor by LITT, facilitates cement fill, enhances biomechanical stability and reduces the risk of cement extravasation.

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“…We have had to rely mainly on observational uncontrolled studies and case series. An overwhelming impression from the results is that the patients are almost immediately relieved of back pain, whether after VP or KP (Barr et al 2000, Lieberman et al 2001, McGraw et al 2002, Coumans et al 2003, Diamond et al 2003, Evans et al 2003, Ledlie and Renfro 2003, McGraw et al 2003, Mehbod et al 2003, Phillips et al 2003, Rao and Singrakhia 2003, Weisskopf et al 2003, Crandall et al 2004, Donovan et al 2004, Grohs and Krepler 2004, Heini and Orler 2004, Hillmeier et al 2004, Masala et al 2004). Most of these reports have shown a short-term success rate of relieving pain of 75-90%.…”

Section: Resultsmentioning

confidence: 97%

“…The method gained further popularity in the United States during the 1990s, mainly for the treatment of osteoporotic fractures. At the end of the millennium, the method was also established in most western European countries (Barr et al 2000, McGraw et al 2002, Diamond et al 2003, Evans et al 2003, Mehbod et al 2003. The VP method was further developed by the introduction of the percutaneous balloon KP technique (Lieberman et al 2001).…”

mentioning

confidence: 99%