Prospective Evaluation of Magnetic Resonance Imaging in the Management of Acute Diabetic Foot Infections

Horowitz, John D.; Durham, Joseph R.; Nease, D. Blaine; Lukens, Matthew L.; Wright, Jonathan; Smead, William L.

doi:10.1007/bf02042659

Cited by 52 publications

(18 citation statements)

References 14 publications

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“…In most recent studies of when classic changes are found in the presence of typical clinical findings [24]. Cross-sectional imaging, i.e., CT scanning, patients with clinically suspected osteomyelitis complicating soft-tissue infection of the foot, MRI has performed better than is more sensitive to cortical bone involvement and better detects bone sequestra in chronic or incompletely treated osteoplain radiography, bone scans, gallium scans, or WBC scans [23, 28,29]. Because of the expense of MRI, however, it myelitis [24].…”

mentioning

confidence: 99%

Osteomyelitis of the Foot in Diabetic Patients

Lipsky¹

1997

CLIN INFECT DIS

323

206

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Osteomyelitis of the foot, a common and serious problem in diabetic patients, results from diabetes complications, especially peripheral neuropathy. Infection generally develops by spread of contiguous soft-tissue infection to underlying bone. The major diagnostic difficulty in diabetic patients is distinguishing bone infection from noninfectious neuropathic bony lesions. Certain clinical signs suggest osteomyelitis, but imaging tests are usually needed. The 111 In-labeled leukocyte scan and magnetic resonance imaging are the most diagnostically useful. Staphylococcus aureus is the most common etiologic agent, followed by other aerobic gram-positive cocci. Aerobic gram-negative bacilli and anaerobes are occasionally isolated, often in mixed infections. Antimicrobial therapy is best directed by cultures of the infected bone, obtained percutaneously or at surgery. Antibiotic therapy should usually be given parenterally, at least initially, and continued for at least 6 weeks. Surgical debridement or resection of the infected bone, when feasible, improves the outcome. With appropriate therapy most cases of osteomyelitis can be successfully managed.

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mentioning

confidence: 99%

Osteomyelitis of the Foot in Diabetic Patients

Lipsky¹

1997

CLIN INFECT DIS

323

206

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“…MR imaging allows precise preoperative localization and evaluation of the extent of fluid collections. This allows the surgeon to plan targeted and limited surgical interventions and avoid potentially harmful empiric explorations (10,11,29).…”

Section: Discussionmentioning

confidence: 99%

Pedal Abscesses in Patients Suspected of Having Pedal Osteomyelitis: Analysis with MR Imaging

Ledermann

Morrison²,

Schweitzer³

2002

Radiology

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“…MR imaging is increasingly used preoperatively to define the extent of deep soft-tissue pedal infection because it enables a targeted surgical approach, thereby limiting damage to surrounding tissue [8][9][10]. However, the potential diagnosis of necrotic tissue on MR imaging has so far not been reported.…”

Section: Cmentioning

confidence: 99%

“…The exact delineation of soft-tissue infection and osteomyelitis on MR images was shown to influence the choice of further therapy [8,9] and to help in planning targeted minimal surgical intervention [6,[8][9][10]. However, to our knowledge no prior reports address the potential of MR imaging to identify necrotic tissue.…”

mentioning

confidence: 93%