Prospective environmental risk assessment of nanocellulose for Europe

Stoudmann, Natasha; Nowack, Bernd; Som, Claudia

doi:10.1039/c9en00472f

Cited by 28 publications

(21 citation statements)

References 49 publications

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“…With increasing use of nanocellulose (NC) in a wide range of industries and applications comes an increased likelihood of human exposure to this material during the various life stages of NC-containing products (Gottschalk and Nowack 2011). NC shows promise within a multitude of application fields, from healthcare to construction (Piccinno et al 2016;Stoudmann, Nowack, and Som 2019). NC can come from many different sources, ranging from wood pulp and cotton to food waste and algae.…”

Section: Introductionmentioning

confidence: 99%

Human hazard potential of nanocellulose: quantitative insights from the literature

et al. 2020

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This review aims to elucidate the current knowledge and future research needs regarding the hazard potential of nanocellulose to human health. Growing interest from research and industry alike has led to increasing likelihood of human contact to the material via various exposure routes. Although a number of comprehensive reviews on human health hazards of nanocellulose have been conducted, this paper brings new insights as it systematically analyzes and quantitatively assesses the results of in vivo and in vitro tests in terms of investigated endpoints, tested concentration ranges, physicochemical properties, surface modifications and source of the tested nanocellulose, exposure route, and cell lines used. The quality of the studies is further inspected based on various established criteria. Considering the rapid development of nanocellulose-based products and the novelty of the material, human health studies remain scarce. By assessing those that have been conducted, patterns and gaps were identified that will be helpful to guide future research. The results show that there are still significant uncertainties remaining, particularly regarding in vivo testing, with pulmonary exposure showing some cause for concern. Although a substantial number of in vitro studies have been undertaken, results are often conflicting. The detected effects could not be directly attributed to size of nanoparticles, cell lines, surface modifications or tested concentrations. This may also be linked to the varying quality of the studies. This review ends by identifying key gaps to help pave the way for future research and ensure the safe development and use of nanocellulose.

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Section: Introductionmentioning

confidence: 99%

Human hazard potential of nanocellulose: quantitative insights from the literature

et al. 2020

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“…According to currently available information, the material poses no risk to human health or the environment. 47 Lignocellulose is a component of the cell walls of wooden plant parts and serves as a structural framework. The material consists of 40-80% cellulose, 5-25% lignin and 10-40% hemicellulose.…”

Section: Nr 52en | February 2020mentioning

confidence: 99%

Polymer Nanocomposites - Additives, properties, applications, environmental aspects (NanoTrust-Dossier No. 052en – February 2020

Greßler¹,

Prenner²,

Kurz³

et al. 2023

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“…Although some LCA analysis have suggested that the inhalation of NC would be the main exposure route for humans, more studies about the exposure concentrations or doses along the different stages, from NC production to customer use, are also required (Shatkin and Kim 2015;. Recently, studies have also quantitative determined the environmental release and risks of NC through the use of probabilistic material flow and environmental risk assessment models (Stoudmann et al 2019).…”

Section: Health Safety and Ecotoxicologymentioning

confidence: 99%

Nanocellulose characterization challenges

Balea

Blanco

Delgado-Aguilar

et al. 2021

BioRes

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Despite the extraordinary properties of nanocellulose (NC), as confirmed through two decades of exhaustive research, addressing an array of potential applications, the NC market is still far from reaching its full potential. Among the main causes is the lack of process-adapted measuring tools capable of characterizing NC, at acceptable speed and reliability, to meet the industrial demands in a cost-effective way. Therefore, reliable characterization methodologies of NC and new standards are of paramount importance in ensuring reproducible research results and quality control specifications for present and future NC products and applications. Furthermore, the successful industrial use of NC products depends on critical parameters that are still being identified and studied. This review paper aims to identify some of the current drawbacks and limitations in NC characterization that hinder their commercial deployment. Moreover, important challenges related to characterization and new opportunities for future research in this field are addressed.

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Prospective environmental risk assessment of nanocellulose for Europe

Abstract: Quantitative environmental risk assessment of nanocellulose, using a dynamic and probabilistic modelling approach. Results show low risk, contributing towards the safe development of this material.

Cited by 28 publications

References 49 publications

Human hazard potential of nanocellulose: quantitative insights from the literature

Human hazard potential of nanocellulose: quantitative insights from the literature

Polymer Nanocomposites - Additives, properties, applications, environmental aspects (NanoTrust-Dossier No. 052en – February 2020

Nanocellulose characterization challenges

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