Prospective cohort study of adverse events monitored by hospital pharmacists

Emerson, Angela; Martin, Richard M; Tomlin, Mark; Mann, Ronald D.

doi:10.1002/pds.574

Cited by 19 publications

(5 citation statements)

References 22 publications

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“…Hospital pharmacists had more favourable attitudes than community pharmacists as they may be more knowledgeable about clinical pharmacy and pharmacovigilance, have access to patient medical records and tend to see more patients with serious ADEs [53–56]. In addition, hospital pharmacists are more directly involved in patient care, and have access to state of the art computer systems which may not be available in the community setting [57, 58]. These factors increase their chances of detecting serious ADEs compared with community pharmacists.…”

Section: Discussionmentioning

confidence: 99%

Influence of attitudes on pharmacists' intention to report serious adverse drug events to the Food and Drug Administration

Gavaza¹,

Brown²,

Lawson³

et al. 2011

Brit J Clinical Pharma

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WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT• Attitude is an important factor impacting pharmacists' reporting of adverse drug events (ADE) to pharmacovigilance centres. • However, little is known about United States (US) pharmacists' attitudes with respect to ADE reporting. No known study has assessed US pharmacists' attitude to report serious ADEs to the FDA. WHAT THIS STUDY ADDS• This study results suggest that pharmacists hold favourable attitudes toward reporting serious ADEs to the FDA and there is an association between pharmacists' attitude and intention to report serious ADEs.• Pharmacists' beliefs that reporting serious ADEs was time consuming and disrupted the normal workflow impact on reporting intentions.• Pharmacists' attitudes towards reporting need to be improved in order to enhance patient and drug safety. AIMTo investigate the influence of pharmacists' attitudes on intention to report serious adverse drug events (ADEs) to the Food and Drug Administration (FDA). METHODSThis cross-sectional study used a mail survey to collect data from hospital and community pharmacists practicing in Texas, United States. Three and 16 items were used to measure intention and attitudes, respectively, using a seven-point bipolar scale. Pharmacists' demographic and practice characteristics, and past reporting were also measured. RESULTSThe response rate was 26.4% (n = 377/1500 pharmacists). Most pharmacists intended (n = 297, 78.8%) to report serious ADEs that they will encounter to the FDA through MedWatch. Overall, pharmacists held favourable attitudes towards reporting serious ADEs (mean = 24.5, SD = 6.7, possible range 1-49, neutral = 16). Pharmacists intending to report serious ADEs had more favourable attitudes than those who did not (P < 0.001). About 90% of the pharmacists believed that reporting serious ADEs would improve patient safety. However, 72.6% indicated that reporting serious ADEs was time consuming and over half (55.5%) of the respondents believed that reporting serious ADEs disrupted the normal workflow. Non-intenders held stronger beliefs that ADE reporting would disrupt the normal workflow and was time consuming compared with intenders. Years of experience, number of hours worked and practice setting were associated with pharmacists' attitudes towards reporting (P < 0.05). CONCLUSIONSMost pharmacists held moderately favourable attitudes and high intentions toward reporting serious ADEs to the FDA. This study's findings contribute to an increased understanding of individual factors that influence pharmacists' attitude and intention towards reporting serious ADEs to the FDA.

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Section: Discussionmentioning

confidence: 99%

Influence of attitudes on pharmacists' intention to report serious adverse drug events to the Food and Drug Administration

Gavaza¹,

Brown²,

Lawson³

et al. 2011

Brit J Clinical Pharma

View full text Add to dashboard Cite

show abstract

“…There is ample evidence that shows that the pharmacist is both willing and capable to adequately fulfil the role of a reporter of ADRs. [25][26][27][38][39][40][41] In addition to this direct role, the pharmacist can also play a coordinating role, both in general practice and in a hospital setting. The fact that in many countries most Table 2.…”

Section: Differences Per Member Statementioning

confidence: 99%

Pharmacists' role in reporting adverse drug reactions in an international perspective

Grootheest

Olsson

Couper

et al. 2003

Pharmacoepidemiology and Drug

141

101

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The appreciation of pharmacists' ADR reports is high in those countries that have more experience with greater numbers of pharmacists' reports. The countries that received fewer reports from pharmacists gave lower scores to their contribution. If the specific contribution pharmacists can make to the quantity and quality of ADR reports were to be exploited to a greater extent, this could lead to a substantial improvement of the international adverse drug reactions reporting system.

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“…Hospital led monitoring systems to report and identify ADRs can also be used along with other spontaneous reporting systems for better monitoring of ADRs as it will provide better understanding of events related to ADR [8]. A study from the UK reported, that although hospital pharmacists were well aware of ADR reporting schemes, were inconsistent in reporting [23].…”

Section: Adr Monitoring Trends In Developed Countriesmentioning

confidence: 99%

“…Pharmacist-led monitoring system at the hospital is effective in detecting ADRs of newly marketed drugs. However, only computer programs not designed as patient focused is not able to identify patients taking newly marketed drugs which should be under strict surveillance [8]. The pharmacist has helped to improve outcomes including reduction in ADRs and medication errors by improving medication adherence through counseling and telephone follow-up which has resulted in identification of preventable adverse drug events.…”

Section: Introductionmentioning

confidence: 99%

Evolving Trends and Future Prospects of Adr Monitoring and Reporting: A Literature Review

Amin

Malik

Hussain

2016

Asian J Pharm Clin Res

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Objective: Owing to the importance of safe use of medicines, adverse drug reaction (ADR) monitoring has become a fundamental component to be performed along with other health-care services. Pharmacist being drug experts are in good position to provide professional assistance for ADR management. The aim of this study is to summarize research findings from developed and developing countries as well as from Pakistan regarding evolving trends and future prospects of ADR monitoring and reporting by pharmacists. Methods: A total of 49 studies were reviewed regarding trends of ADR monitoring using different search engines including google scholar, pubmed and science direct. Results: The review highlighted that there is need to identify the barriers and gaps to further enhance the effectiveness of current ADR monitoring practices. Conclusion: Strong legislation is required in Pakistan to develop and implement an effective ADR monitoring program to reinforce the conception of effective pharmacovigilance system in Pakistan.

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Prospective cohort study of adverse events monitored by hospital pharmacists

Cited by 19 publications

References 22 publications

Influence of attitudes on pharmacists' intention to report serious adverse drug events to the Food and Drug Administration

Influence of attitudes on pharmacists' intention to report serious adverse drug events to the Food and Drug Administration

Pharmacists' role in reporting adverse drug reactions in an international perspective

Evolving Trends and Future Prospects of Adr Monitoring and Reporting: A Literature Review

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