Prospective analysis of endocrine function in children with residual/recurrent low-grade brain tumours treated with high-precision stereotactic conformal radiotherapy

Dutta, Debnarayan; Shah, N.; Gupta, Tejpal; Munshi, Atul; Jalali, Rakesh

doi:10.1200/jco.2008.26.15_suppl.2049

Cited by 1 publication

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“…More than half of patients with low-grade brain tumors before radiotherapy have been shown to have hormone deficiency in at least one axis, with maximum deficiency seen in sellar tumors and only 3/57 patients needed an additional hormone after treatment with modern stereotactic conformal radiotherapy. [35] Radiation-induced optic neuropathy is virtually unknown now in clinical practice with the doses, fractionation and techniques employed. Risk of cerebrovascular accident and radionecrosis are seen in approximately 1% of patients.…”

Section: Chronic Toxicities In Cancer Survivorsmentioning

confidence: 99%

Curability of cancer by radiotherapy and chemotherapy, including in neuraxial neoplasms

2009

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In the October of 1996, Lance Armstrong, celebrated cyclist and one of the greatest athletes the world has ever seen, at the age of 24, was diagnosed with metastatic testicular cancer with disease having already spread to his abdomen, lungs and brain. Lance underwent four cycles of chemotherapy, actually the pretty standard one, pioneered at the Indiana University and not only did he get completely cured of his cancer, he remains extremely well till date, 12 years later. He sure did have a few adverse effects during those cycles of chemotherapy in the form of nausea, vomiting, weakness and fall in blood count but he knew and experienced them only for a short transient time and emerged triumphant and strong. In fact, he went on to win six awe-inspiring and incredible successive Tours de France victories from 1999-2005, one of the most grueling sporting events testing the endurance of the very fittest. After his retirement, he has been so inspired that he has completely devoted himself to educate people about the common myths about cancer, and promised to raise awareness and generate money for furthering research into surgery, radiation therapy and chemotherapy for cancer through his foundation. He says "I am indebted to the doctors, nurses and medicine and would want to pay them back for all their energy and caring." In his successful journey of overcoming cancer, he captures the essence of its treatment so well by declaring "Pain is temporary, it may last a minute, or an hour, or a day, or a year, but eventually, it will subside and something else will take its place. If I quit, however, it will last forever".

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Section: Chronic Toxicities In Cancer Survivorsmentioning

confidence: 99%