Prospecting for Bioactive Constituents from Traditional Medicinal Plants through Ethnobotanical Approaches

Gu, Ronghui; Wang, Yue-Hu; Long, Bo; Kennelly, Edward J.; Wu, Shi‐Biao; Liu, Bo; Li, Ping; Li, Chunlin

doi:10.1248/bpb.b14-00084

Cited by 60 publications

(27 citation statements)

References 65 publications

(108 reference statements)

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“…3 and Table 3). Plants contains variety of phytochemical components, many of them are biologically active compounds and known to have pharmacological activities (Gu et al, 2014). The bioactive secondary metabolites have been shown to reduce the risk and progression of diseases such as cancer, cardiovascular disease, neurodegenerative diseases, etc by scavenging free radicals through various biological mechanism (Ansari and Khodagholi, 2013).…”

Section: Resultsmentioning

confidence: 99%

Identification of Volatile Compound in Coconut Milk Samples Using GC-MS

Kokilavani¹,

Sashidevi²,

Venilla³

et al. 2017

Int.J.Curr.Microbiol.App.Sci

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Section: Resultsmentioning

confidence: 99%

Identification of Volatile Compound in Coconut Milk Samples Using GC-MS

Kokilavani¹,

Sashidevi²,

Venilla³

et al. 2017

Int.J.Curr.Microbiol.App.Sci

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“…many of which are known to be biologically active compounds and are responsible for exhibiting diverse pharmacological activities 16 . Numerous reports available on phenolic compounds have demonstrated their usefulness in exhibiting potential biological activities such as antioxidant, antidiabetic, hepatoprotective, anti-inflammatory, antimicrobial, anticancer 17 etc.…”

Section: Discussionmentioning

confidence: 99%

Phytochemical Screening and Gc-MS Analysis of Methanolic Extract of Bombax Ceiba Bark

Selvaraju¹,

Beldal²,

Londonkar³

2018

Int. Res. J. Pharm.

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Preliminary screening of phytochemicals is a valuable step, in the detection of the bioactive principles present in medicinal plants and subsequently it will lead to drug discovery and development. The present effort has been intended to investigate the phytochemical constituents, quantify the total phenolic and flavonoid contents and to determine the possible bioactive components of methanolic bark extract of Bombax Ceiba using GC-MS analysis. Phytochemical screening of bark extract revealed the presence of around 30 compounds such as alkaloid, carbohydrates, tannins, steroids, flavonoids, glycosides and phenolic compounds. Amongst these it was found to contain the highest phenolic content and flavonoids content. The compounds were identified by comparing their retention time, peak area and by interpretation of mass spectra and matched with the National Institute of Standards and Technology (NIST) library. The Bombax ceiba shows it is an excellent source of phytocomponents, which are medicinal important to become a potential drug in future perspective. Isolation of individual components would however, help to find new drugs.

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“…22 According to the previous records of pharmacognosy sciences plants have been used in native medicinal systems globally. Medicinal plant based research are rapidly increasing worldwide and further study with emphasis on efficiency, safety and quality of plant secondary metabolites is the need of the hour.…”

Section: Discussionmentioning

confidence: 99%

Pharmacognostic, Phytochemical and Physicochemical Investigations of Hypericum hookerianum Wight & Arn. (Hypericaceae) of Palni Hills, India

Mahendrakumar¹,

Nirmalraj²,

Ravikumar³

et al. 2017

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Introduction:Hypericum hookerianum Wight and Arn. (Hooker's wort) is a lesser known unfamiliar yet critically endangered native therapeutically active native medicinal plant. It is being characterized by the presence of various secretory glands. Methodology: In this present study, characterization of the plant in terms of morphology, anatomy and histochemistry of tissues and phytochemicals and antimicrobial potentials were made. Results: The epidermal layer contains oil cells while histochemistry showed the presence of the secondary metabolites. Qualitative analysis indicated presence of maximum phytocompounds in the high polar ethanolic extract; flavonoids, anthocyanin and phenol are prominently present and quantified. Conclusion:The results suggest that the less studied herb, H. hookerianum is a multifaceted high value species having a wide range of phytochemicals with abundant medicinal properties. Key words: Hypericum hookerianum, Pharmacognosy, Physiochemistry, Palni Hills. The terete shrubs are 2-2.5 m in height, with rather flaccid ovate leaves, set bifarious, mucronate to mucronate at apex. 2 The tribal people of the Shola forest (Tamil Nadu) in Palni hills use the aerial parts of the plant for treating burns and wounds demonstrated by Mukherjee and Suresh. 3 to have wound healing properties. The Toda tribe of the Palni hills uses it as a folklore medicine for its different therapeutic potentials, including antidepressant, spasmolytic, stimulant, hypotensive and antifungalactivities. 4 Leaf anatomy of hypericum species differ greatly and is the basis for not only identifying the species but also grouping them under different taxonomic criteria. Anatomical features in terms of types of glands present, secretions of the glands, interconnecting and extension of the ducts, quality of the products of the secretory glands and phytochemical profiles of the secretion play an important in differentiating the species. The anatomy and ultra-structure of the cavities in the internodes, leaves and petals varied extensively between species of Hypericum, especially in H. hookerianum. The secondary growth is more extensive in shrubs (H. inodorum and H. forestii). The petals also differ between species in the mesophyll structures and the occurrence and location of secondary structures.5 It is against this background, the pharmacognostic profile, anatomy of the secretory Fluorescence EvaluationThe fluorescence analysis of the dried leaf powder was carried out by the method of Kokoski et al. 14 A small quantity of the sample treated using fluorescence reagents (such as 1 N NaOH, 1 N HCl, 50% H 2 SO 4 , FeCl 3 , Iodine Solution, Acetic Acid Glacial, 0.1N NH 4 OH, 1 % CH 3 COOH) and analyzed under visible light and ultra violet light (Wavelength 254 nm). Phytochemical determinationThe dried leaf powder of H. hookerianum was extracted successively with different polarity solvents such as Hexane, Ethyl Acetate and Ethanol. After 24 hours, the dried extracts were obtained and were analyzed using chemical re...

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Prospecting for Bioactive Constituents from Traditional Medicinal Plants through Ethnobotanical Approaches

Cited by 60 publications

References 65 publications

Identification of Volatile Compound in Coconut Milk Samples Using GC-MS

Identification of Volatile Compound in Coconut Milk Samples Using GC-MS

Phytochemical Screening and Gc-MS Analysis of Methanolic Extract of Bombax Ceiba Bark

Pharmacognostic, Phytochemical and Physicochemical Investigations of Hypericum hookerianum Wight & Arn. (Hypericaceae) of Palni Hills, India

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