Prospect of Gum Arabic–Cocoliposome Matrix to Encapsulate Curcumin for Oral Administration
Dwi Hudiyanti,
Muhammad Fuad Al Khafiz,
Khairul Anam
et al.
Abstract:Curcumin is an antioxidant that can effectively eliminate free radicals. However, as its oral bioavailability is low, an effective delivery method is required. Phospholipid-based liposomes can encapsulate lipophilic drugs, such as curcumin, while liposome, cholesterol, and gum Arabic (GA) can enhance the internal and external stability of drug membranes. This present study used concentrations of cholesterol (Cchol) and GA (CGA), ranging from 0 to 10, 20, 30, and 40% as well as 0 to 5, 10, 15, 20, 30, and 40%, … Show more
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