2018
DOI: 10.5455/medarh.2018.72.136-140
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Proprietary Herbal Extract Downregulates the Gene Expression of Il-1 and #945; in HaCaT Cells: Possible Implications Against Nonscarring Alopecia

Abstract: BackgroundCurrently while, topical minoxidil and oral finasteride are the only medications approved in androgenetic alopecia (AGA), the cause oriented treatment and immunsupressive treatment are being performed in telogen effluvium (TE) and alopecia areata (AA) respectively. Considering the inflammatory factors in the pathogenesis of these three nonscarring alopecia forms, we have formulated a mixture for topical usage composed of six different herbal extracts (HE) which have already known antiinflammatory and… Show more

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Cited by 8 publications
(6 citation statements)
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“…Pods aqueous extract (with 5 other plants) downregulated IL-1α in HaCaT cells, suggesting nonscarring hair loss prevention activity [24].…”
Section: Anti-alopeciamentioning
confidence: 99%
“…Pods aqueous extract (with 5 other plants) downregulated IL-1α in HaCaT cells, suggesting nonscarring hair loss prevention activity [24].…”
Section: Anti-alopeciamentioning
confidence: 99%
“…Viu-se que o epigalocatequina-3-galato é mais seguro e mais específico que os inibidores da JAK. Pekmezci, et al, 2018. Imunoensaio clínico feito com cultura de células HaCat in vitro a partir de pele histologicamente normal. Nessas células foi usado um conjunto de extratos herbais.…”
Section: Rodgers 2018unclassified
“…As ervas usadas foram: extrato de raiz de Urtica dioica, extrato de folha de Urtica urens, extrato de folha do Equisetum arvense, extrato da parte aérea de Achillea millefolium, extrato da folha de Matricaria chamomilla e extrato do fruto de Ceratonia siliqua. O extrato foi usado em cultura de células HaCat in vitro retiradas da pele histologicamente normal, essas foram submetidas a diferentes concentrações da solução de ervas (Pekmezci, Dundar & Turkoglu, 2018).…”
Section: Rodgers 2018unclassified
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“…In addition, nettle extract is used as a source of natural green color (natural dye) or pigment of natural origin for coloring soaps and shampoos, cosmetics, various lotions, toothpastes, antibacterial mouthwashes, and edible fats ( 7 ). It is used for sparse and weak hair, prevents alopecia ( 31 ).…”
Section: Introductionmentioning
confidence: 99%