Propranolol treatment for subglottic haemangioma

Guye, E.; Chollet-Rivier, Madeleine; Schröder, D; Sandu, Kishore; Hohlfeld, Judith; Roessingh, Anthony de Buys

doi:10.1136/adc.2010.201905

Cited by 6 publications

(4 citation statements)

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“…The primary exclusion criterion was the use of any intervention or medical therapy prior to propranolol. Twenty‐four studies published between 2009 and 2016 met all inclusion criteria to be included in the final review and analysis . Although our search began with articles in 2008, the first study meeting our inclusion criteria of primary treatment with propranolol was not published until 2009.…”

Section: Resultsmentioning

confidence: 99%

Efficacy and rebound rates in propranolol‐treated subglottic hemangioma: A literature review

et al. 2017

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Section: Resultsmentioning

confidence: 99%

Efficacy and rebound rates in propranolol‐treated subglottic hemangioma: A literature review

et al. 2017

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“…Le tableau I recense plusieurs de ces études, avec les principaux résultats. [11][12][13][14][15][16][17][18][19][20][21][22][23][24][25] Malheureusement, bien souvent, la faible taille de la cohorte étudiée rend difficile toute extrapolation. Récemment, une méta-analyse a comparé l'efficacité du propranolol vis-à-vis des traitements actuels (corticostéroïdes, laser, vincristine) du propranolol sur l'hémangiome des voies aériennes supérieures chez l'enfant.…”

Section: Efficacité Du Propranololunclassified

Mise au point sur le traitement de l’hémangiome du nourrisson par bêta-bloquant

et al. 2012

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Hemangiomas are benign tumors most commonly encountered in infancy and early childhood. While most of them regress spontaneously, some require treatment due to a significant proliferation, which may be complicated by ulceration, deformation aesthetic deformation or worse impairment vital. Among the treatments used corticosteroids is the standard treatment but its use in high doses expose to potential risks. In 2008, the discovery by "chance" of the effectiveness of propranolol in the management of hemangioma revolutionizes the first line treatment. Its mechanism of action is not yet well understood and establishment of such treatment should be done by a hospital paediatrician in the absence of any contraindications. This article proposes focus on effectiveness and tolerance of β-blockers used as treatment of infantile hemangiomas.

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“…A follow-up retrospective study in France showed that propranolol effectively reduced 37 of 39 head and neck hemangiomas, and advocated propranolol as a first line treatment for head and neck hemangiomas. Since that time, there have been several successful reports of propranolol use for airway hemangiomas, either as part of a combined therapy with corticosteroids [2][3][4], or as isolated therapy [5][6][7][8]. Leboulangier published a series of 14 patients with subglottic hemangioma recalcitrant to other forms of treatment, all of whom responded to propranolol therapy initially [9].…”

Section: Introductionmentioning

confidence: 96%